Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 4 de 4
Filter
Add more filters










Database
Language
Publication year range
1.
Med Educ ; 43(11): 1062-8, 2009 Nov.
Article in English | MEDLINE | ID: mdl-19874499

ABSTRACT

CONTEXT: Emotional intelligence (EI), the ability to perceive emotions in the self and others, and to understand, regulate and use such information in productive ways, is believed to be important in health care delivery for both recipients and providers of health care. There are two types of EI measure: ability and trait. Ability and trait measures differ in terms of both the definition of constructs and the methods of assessment. Ability measures conceive of EI as a capacity that spans the border between reason and feeling. Items on such a measure include showing a person a picture of a face and asking what emotion the pictured person is feeling; such items are scored by comparing the test-taker's response to a keyed emotion. Trait measures include a very large array of non-cognitive abilities related to success, such as self-control. Items on such measures ask individuals to rate themselves on such statements as: 'I generally know what other people are feeling.' Items are scored by giving higher scores to greater self-assessments. We compared one of each type of test with the other for evidence of reliability, convergence and overlap with personality. METHODS: Year 1 and 2 medical students completed the Meyer-Salovey-Caruso Emotional Intelligence Test (MSCEIT, an ability measure), the Wong and Law Emotional Intelligence Scale (WLEIS, a trait measure) and an industry standard personality test (the Neuroticism-Extroversion-Openness [NEO] test). RESULTS: The MSCEIT showed problems with reliability. The MSCEIT and the WLEIS did not correlate highly with one another (overall scores correlated at 0.18). The WLEIS was more highly correlated with personality scales than the MSCEIT. CONCLUSIONS: Different tests that are supposed to measure EI do not measure the same thing. The ability measure was not correlated with personality, but the trait measure was correlated with personality.


Subject(s)
Clinical Competence/standards , Education, Medical, Undergraduate/standards , Emotional Intelligence , Psychological Tests/standards , Students, Medical/psychology , Adult , Communication , Emotions , Female , Humans , Male , Reproducibility of Results , Young Adult
2.
J Occup Health Psychol ; 12(4): 319-33, 2007 Oct.
Article in English | MEDLINE | ID: mdl-17953492

ABSTRACT

This survey study of 176 participants from eight customer service organizations investigated how individual factors moderate the impact of emotional labor strategies on employee well-being. Hierarchical regression analyses indicated that gender and autonomy were significant moderators of the relationships between emotional labor strategies and the personal outcomes of emotional exhaustion, affective well-being, and job satisfaction. Females were more likely to experience negative consequences when engaging in surface acting. Autonomy served to alleviate negative outcomes for individuals who used emotional labor strategies often. Contrary to our hypotheses, emotional intelligence did not moderate the relationship between the emotional labor strategies and personal outcomes. Results demonstrated how the emotional labor process can influence employee well-being.


Subject(s)
Employment/psychology , Intelligence , Job Satisfaction , Occupational Health , Professional Autonomy , Adult , Affect , Burnout, Professional/epidemiology , Cognitive Dissonance , Commerce , Emotions , Expressed Emotion , Female , Humans , Interpersonal Relations , Male , Middle Aged , Role Playing , Sex Factors , Social Environment , Universities
3.
J Bacteriol ; 189(2): 591-602, 2007 Jan.
Article in English | MEDLINE | ID: mdl-17114254

ABSTRACT

To address the need for new antibacterials, a number of bacterial genomes have been systematically disrupted to identify essential genes. Such programs have focused on the disruption of single genes and may have missed functions encoded by gene pairs or multiple genes. In this work, we hypothesized that we could predict the identity of pairs of proteins within one organism that have the same function. We identified 135 putative protein pairs in Bacillus subtilis and attempted to disrupt the genes forming these, singly and then in pairs. The single gene disruptions revealed new genes that could not be disrupted individually and other genes required for growth in minimal medium or for sporulation. The pairwise disruptions revealed seven pairs of proteins that are likely to have the same function, as the presence of one protein can compensate for the absence of the other. Six of these pairs are essential for bacterial viability and in four cases show a pattern of species conservation appropriate for potential antibacterial development. This work highlights the importance of combinatorial studies in understanding gene duplication and identifying functional redundancy.


Subject(s)
Genes, Bacterial/genetics , Genes, Duplicate , Genes, Essential/genetics , Amino Acid Sequence , Bacillus subtilis/genetics , Bacillus subtilis/growth & development , Bacterial Proteins/genetics , Bacterial Proteins/physiology , Computational Biology , Gene Deletion , Gene Duplication , Gene Expression Regulation, Bacterial , Genes, Bacterial/physiology , Genes, Essential/physiology , Genome, Bacterial , Molecular Sequence Data , Mutation , Sequence Alignment
4.
J Biol Chem ; 280(48): 39709-15, 2005 Dec 02.
Article in English | MEDLINE | ID: mdl-16174771

ABSTRACT

The continuous emergence of antibiotic resistance demands that novel classes of antibiotics continue to be developed. The division machinery of bacteria is an attractive target because it comprises seven or more essential proteins that are conserved almost throughout the bacteria but are absent from humans. We describe the development of a cell-based assay for inhibitors of cell division and its use to isolate a new inhibitor of FtsZ protein, a key player in the division machinery. Biochemical, cytological, and genetic data are presented that demonstrate that FtsZ is the specific target for the compound. We also describe the effects of more potent analogues of the original hit compound that act on important pathogens, again at the level of cell division. The assay and the compounds have the potential to provide novel antibiotics with no pool of pre-existing resistance. They have provided new insight into cytokinesis in bacteria and offer important reagents for further studies of the cell division machinery.


Subject(s)
Anti-Infective Agents/pharmacology , Cytokinesis/drug effects , Drug Resistance, Bacterial , Microbial Sensitivity Tests/methods , Phenyl Ethers/pharmacology , beta-Alanine/analogs & derivatives , Bacillus subtilis , Bacterial Proteins/metabolism , Cell Division , Cloning, Molecular , Cytoskeletal Proteins/metabolism , Dose-Response Relationship, Drug , GTP Phosphohydrolases/metabolism , Genes, Reporter , Green Fluorescent Proteins , Models, Molecular , Mutation , Phenotype , Temperature , Time Factors , beta-Alanine/pharmacology
SELECTION OF CITATIONS
SEARCH DETAIL
...