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1.
Spine (Phila Pa 1976) ; 32(13): 1444-9, 2007 Jun 01.
Article in English | MEDLINE | ID: mdl-17545914

ABSTRACT

STUDY DESIGN: Survey. OBJECTIVE: To understand the variation in scoliosis surgery and perioperative care among spinal deformity surgeons. SUMMARY OF BACKGROUND DATA: While variation in care has been well described in many spinal disorders, the degree of variation has not been described for spinal deformity. METHODS: Clinical histories and radiographs of 4 typical spinal deformity patients were sent to spinal deformity surgeons for review. The cases consisted of idiopathic thoracolumbar, double major, and right thoracic curves and a neuromuscular lumbar curve. The survey queried choice of surgical approach, levels fused and instrumented, type of instrumentation, preoperative testing, intraoperative neurologic monitoring, blood and antibiotic use, and postoperative care, including pain control and patient mobilization. Cost estimates for each case were obtained from the individual hospitals' pricing. RESULTS: There was wide variation in the specific fusion levels and instrumentation for the idiopathic curves. The variation was greatest for the thoracolumbar curve. The double major and right thoracic curves differed primarily in their choice of instrumenting secondary curves. The neuromuscular curve had the least variation. Costs estimates were widely disparate between centers. Perioperative care had much less disparity. CONCLUSIONS: Agreement appears common in areas with readily identifiable outcomes such as shorter length of stay and rapid postoperative mobilization. However, agreement is poor in areas where outcomes are difficult to measure and require long-term follow-up such as instrumentation fusion and levels.


Subject(s)
Health Care Surveys , Orthopedics/standards , Pediatrics/standards , Scoliosis/surgery , Surgery Department, Hospital/standards , Adolescent , Child , Female , Humans , Length of Stay , Lumbar Vertebrae/surgery , Male , Organizations, Nonprofit/economics , Organizations, Nonprofit/standards , Orthopedics/economics , Pediatrics/economics , Scoliosis/economics , Spinal Fusion , Surgery Department, Hospital/economics , Thoracic Vertebrae/surgery
2.
Am J Med Sci ; 329(5): 217-21, 2005 May.
Article in English | MEDLINE | ID: mdl-15894862

ABSTRACT

OBJECTIVE: We hypothesized that functional mitral and tricuspid valvular incompetence (MR and TR, respectively) are reversible causes of reduced cardiac output in decompensated heart failure (DF) that accompanies systolic dysfunction in ischemic or nonischemic cardiomyopathy. BACKGROUND: DF, defined as signs and symptoms of heart failure at rest, is rooted in a salt-avid state transduced by neurohormonal activation secondary to impaired renal perfusion. Functional MR and TR are reversible causes of reduced systemic blood flow. Their impact on cardiac output, thoracic fluid content, cardiac chamber dimensions, and valvular apparatus function can be monitored noninvasively, before and after optimized medical management. METHODS: Fourteen male subjects (66 +/- 8 years old) with reduced ejection fraction (24 +/- 5%) secondary to ischemic (71%) or nonischemic (29%) cardiomyopathy, who developed DF with clinical evidence of mitral (MR) and tricuspid (TR) valvular incompetence, were each assessed by bioimpedance and echocardiography before and 1 week after optimized medical management restored compensated failure. RESULTS: Pharmacologic elimination of DF was accompanied by a reduction in body weight (P < 0.01). Hemodynamic improvements included a rise in cardiac index (2.1 to 2.6 L/min/m2; P < 0.01) and a reduction in predicted pulmonary artery systolic pressure (58 to 35 mm Hg; P < 0.001), thoracic fluid content (39 to 32 kOhm; P < 0.001), and systemic vascular resistance (1633 to 1209 dynes/sec/cm5; P < 0.001). Improvements in functional MR and TR included reductions in left and right atrial areas (27 to 24 cm and 26 to 23 cm2, respectively; P < 0.001), color-flow grading of MR and TR severity (P < 0.01), mitral regurgitant volume (105 to 65 mL; P < 0.001), and effective MR orifice size (0.8 to 0.6 cm2; P < 0.01). CONCLUSIONS: In DF, functional MR and TR contribute to reduced cardiac output, increased thoracic fluid content, and systemic vascular resistance, together with enlarged atria and valvular orifice size, which can be improved by medical management. Bioimpedance and echocardiography provide for serial noninvasive assessments of hemodynamic status and valvular function in such cases.


Subject(s)
Heart Failure/physiopathology , Mitral Valve Insufficiency/physiopathology , Tricuspid Valve Insufficiency/physiopathology , Aged , Body Fluids/metabolism , Cardiac Output , Cardiography, Impedance , Echocardiography , Heart Failure/diagnostic imaging , Heart Failure/etiology , Humans , Male , Mitral Valve Insufficiency/complications , Mitral Valve Insufficiency/diagnostic imaging , Thoracic Cavity/metabolism , Tricuspid Valve Insufficiency/complications , Tricuspid Valve Insufficiency/diagnostic imaging , Vascular Resistance
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