ABSTRACT
While blindness is one of the typical clinical presentations of temporal arteritis, tongue necrosis, on the other hand, is an unusual complication of the disease. An 80 year old male patient presenting a sudden massive swelling of the tongue was admitted to the Hospital of Yverdon. The swelling rapidly progressed to a complete necrosis of the tongue within a few days. The clinical presentation, the dramatic evolution of the necrosis, and sudden unilateral blindness despite prompt treatment confirmed our diagnosis of temporal arteritis. However, all the examinations, including biopsy of the right temporal artery, remained non-specific for the disease. Our diagnosis was based on the unusual clinical presentation of the disease.
Subject(s)
Blindness/diagnostic imaging , Giant Cell Arteritis/diagnostic imaging , Ischemia/diagnostic imaging , Tongue/blood supply , Ultrasonography, Doppler, Duplex , Aged , Aged, 80 and over , Diagnosis, Differential , Humans , Male , Necrosis , Tongue/pathologySubject(s)
Q Fever/complications , Respiratory Distress Syndrome/microbiology , Adult , Anti-Bacterial Agents/therapeutic use , Combined Modality Therapy , Female , Humans , Long-Term Care , Q Fever/diagnosis , Q Fever/immunology , Q Fever/therapy , Respiration, Artificial/methods , Respiratory Distress Syndrome/diagnosis , Respiratory Distress Syndrome/therapy , Serologic TestsABSTRACT
Rhodococcus equi (R. equi) has been reported as an occasional cause of pulmonary infection in severely immunocompromised hosts, including AIDS patients. Our purpose is to describe the radiologic findings in two AIDS patients with R. equi pneumonia. Chest radiographs showed right-upper-lobe consolidation and cavitation in both patients. Chest CT confirmed upper mediastinal involvement and precarinal lymphadenopathy in both cases. Multiple lung nodules related to the bronchi were also identified in one patient. In an AIDS patient from a rural area or with exposure to horses, the possibility of R. equi infection should be considered when cavitary pneumonia is present, even if there is mediastinal involvement and/or lymphadenopathy, or if multiple lung nodules are also present.
Subject(s)
AIDS-Related Opportunistic Infections/diagnostic imaging , Actinomycetales Infections/diagnostic imaging , Pneumonia, Bacterial/diagnostic imaging , Rhodococcus equi , Adult , Female , Humans , Male , Radiography, Thoracic , Tomography, X-Ray ComputedABSTRACT
A young man who had suffered several episodes of deep-vein thrombosis of the legs since the age of 20 had a myocardial infarction at the age of 33, at which time both a prolonged partial thromboplastin time (PTT), compatible with a lupus anticoagulant (LA), and decreased fibrinolytic capacity (FC) were found. His sister presented with deep-vein thrombosis of a leg and subsequent pulmonary embolism when she was 18 years old. She had a miscarriage three years later and developed a hemolytic-uremic syndrome at the age of 35. The PT and FC were normal. Laboratory investigations of the parents revealed positive antinuclear antibodies in the mother's serum but no anomaly in the father. This study suggests a familial tendency to develop autoimmune disorders associated with LA and thromboembolic complications related to decreased FC.
