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1.
Osteoarthritis Cartilage ; 29(12): 1691-1700, 2021 12.
Article in English | MEDLINE | ID: mdl-34571138

ABSTRACT

OBJECTIVE: To characterize the differences and correlations in osteophyte volumes between and within proximal tibial compartments, and to assess the correlations between osteophyte volumes and the femorotibial angle. DESIGN: CT scans of 73 knees with predominantly medial femorotibial osteoarthritis (21 K/L2, 28 K/L3, 24 K/L4) were retrospectively analyzed using a new, reproducible method measuring total and subregional osteophyte volumes in the medial and lateral compartments. Non-parametric statistics was used for comparison and correlation analyses. RESULTS: Total osteophyte volumes were larger in the medial than in the lateral compartment for all severity groups (p < 0.05). Additionally, statistically significant differences were observed among subregions of the lateral compartment in K/L3 and K/L4 knees. Statistically significant positive correlations were found between the medial and lateral total osteophyte volumes in K/L3 and K/L4 knees (ρ ≥ 0.44, p = 0.03), and among most subregional osteophyte volumes within each compartment in K/L3 knees. Markedly fewer statistically significant correlations were present in K/L2 and K/L4 knees. In K/L3 knees, the femorotibial angle was statistically significantly positively correlated with the total osteophyte volume in the medial compartment (ρ = 0.50, p = 0.01), with osteophyte volumes in most medial subregions, and with the osteophyte volume in the lateral posterior subregion (ρ = 0.40, p = 0.05). CONCLUSIONS: Quantitative assessment of osteophytes may bring insight on factors influencing their development. Positive correlations of osteophyte volumes found between and within compartments suggest the influence of biochemical mediators acting on the entire joint, while positive correlations between the femorotibial angle and osteophyte volumes suggest a role of mechanical factors. These hypotheses are to be further confirmed.


Subject(s)
Knee Joint/diagnostic imaging , Osteoarthritis, Knee/diagnostic imaging , Osteophyte/diagnostic imaging , Aged , Computer Simulation , Cross-Sectional Studies , Female , Humans , Imaging, Three-Dimensional , Male , Middle Aged , Retrospective Studies , Severity of Illness Index , Tomography, X-Ray Computed
2.
Gait Posture ; 77: 293-299, 2020 03.
Article in English | MEDLINE | ID: mdl-32120246

ABSTRACT

BACKGROUND: Lately, the projection of foot placement visual cues onto the floor has been considered for use in gait rehabilitation. While promising, this approach needs further basic assessment to ensure proper uses. RESEARCH QUESTION: Does following floor-projected foot placement visual cues of one's natural walking pattern induce gait mechanics changes immediately or after a practice period? METHODS: Gait mechanics data from fifteen healthy individuals (7 female, 25.4 ±â€¯5.0 years, 21.5 ±â€¯1.68 kg/m2) was collected during normal walking without visual cues, and during two testing phases (immediate and after 45-60 min of practice) of walking with floor-projected visual cues depicting their normal spatial parameters. Magnitudes and variabilities of spatial gait parameters and sagittal plane lower limb kinematics and kinetics were compared between the three testing phases using repeated measures ANOVA and post-hoc paired t-tests. RESULTS: Compared to normal walking without foot placement visual cues, there was a statistically significant (p < 0.05) increase in stride length (maximum change of 0.01 ±â€¯0.01 m), stance phase knee flexion (2.0 ±â€¯2.5°), and swing phase hip flexion (1.2 ±â€¯1.3°) in both immediate and post-practice testing phases, along with an increase in terminal stance hip (0.28 ±â€¯0.38 %BW*Ht) and knee (0.25 ±â€¯0.25 %BW*Ht) flexion moments in the immediate testing phase. All of these changes between testing phases were smaller than their corresponding normal gait smallest real differences (SRD). With the addition of visual cues, variability was statistically significantly decreased in spatial parameters and increased in knee flexion angle at heel strike and knee flexion moment in terminal stance. SIGNIFICANCE: While biomechanical changes were observed, their magnitudes were small enough to suggest that floor-projected visual cues can be used in gait retraining without introducing unintended gait changes. Furthermore, the results suggested that lengthy practice periods are not necessary. The validity of these observations will, however, need to be confirmed in cases of severe impairments.


Subject(s)
Cues , Foot/physiology , Gait/physiology , Lower Extremity/physiology , Visual Perception/physiology , Adult , Biomechanical Phenomena , Female , Healthy Volunteers , Humans , Kinetics , Male , Rehabilitation
3.
Osteoarthritis Cartilage ; 27(4): 621-629, 2019 04.
Article in English | MEDLINE | ID: mdl-30611905

ABSTRACT

OBJECTIVE: To test whether subchondral bone mineral density (sBMD) and cartilage thickness (CTh) of femoral condyles are correlated in knees without and with severe medial femorotibial osteoarthritis (OA), using a subregional analysis with computerized tomography (CT) arthrography. METHODS: CT arthrograms of 50 non-OA (18 males, 58.7 (interquartile range (IQR) = 6.6 years)) and 50 severe medial OA (24 males, 60.5 (IQR = 10.7) years) knees, were retrospectively analyzed. Bone and cartilage were segmented using custom-designed software, leading to 3D models on which each point of the subchondral surface is given a CTh and sBMD value. The average sBMD and CTh were then calculated for the entire weight-bearing regions as well as specific subregions of interest. Linear bivariate and multivariable analyses were performed to test for relationships between sBMD and CTh (regional and subregional measures, or medial-to-lateral ratios), with confounders of age, gender, femoral bone size and femorotibial angle. RESULTS: In non-OA knees, the sBMD and CTh medial-to-lateral ratios were positively correlated for the total region and the external and internal subregions (r ≥ 0.341, P ≤ 0.015). In OA knees, sBMD and CTh medial-to-lateral ratios were negatively correlated for the total region and the external and central subregions (r ≤ -0.538, P < 0.001). Additional positive/negative relationships in the non-OA/OA knees were observed between sBMD and CTh measures in the medial compartment. CONCLUSIONS: The positive correlation between sBMD and CTh in non-OA knees, and the negative one in OA knees, bring support to the theory of a subchondral bone/cartilage functional unit, which could help to better understand the pathophysiology of OA.


Subject(s)
Algorithms , Arthrography/methods , Cartilage, Articular/diagnostic imaging , Imaging, Three-Dimensional/methods , Osteoarthritis, Knee/diagnosis , Tomography, X-Ray Computed/methods , Bone Density , Child , Cross-Sectional Studies , Female , Follow-Up Studies , Humans , Male , Retrospective Studies
4.
Osteoarthritis Cartilage ; 26(11): 1425-1437, 2018 11.
Article in English | MEDLINE | ID: mdl-30056214

ABSTRACT

OBJECTIVE: To introduce an integrated joint system (IJS) model of joint health and osteoarthritis (OA) pathophysiology through a systematic review of the cross-sectional relationships among three knee properties (cartilage thickness, gait mechanics, and subchondral bone mineral density). METHODS: Searches using keywords associated with the three knee properties of interest were performed in PubMed, Scopus, and Ovid databases. English-language articles reporting cross-sectional correlations between at least two knee properties in healthy or tibiofemoral OA human knees were included. A narrative synthesis of the data was conducted. RESULTS: Of the 5600 retrieved articles, 13 were included, eight of which reported relationships between cartilage thickness and gait mechanics. The 744 tested knees were separated into three categories based on knee health: 199 healthy, 340 at-risk/early OA, and 205 late OA knees. Correlations between knee adduction moment and medial-to-lateral cartilage thickness ratios were generally positive in healthy, inconclusive in at-risk/early OA, and negative in late OA knees. Knee adduction moment was positively correlated with medial-to-lateral tibial subchondral bone mineral density ratios in knees of all health categories. One study reported a positive correlation between lateral tibial subchondral bone mineral density and femoral cartilage thickness in at-risk/early OA knees. CONCLUSIONS: The correlations identified between knee properties in this review agreed with the proposed relationship-based IJS model of OA pathophysiology. Accordingly, the IJS model could provide insights into overcoming current barriers to developing disease-modifying treatments by considering multiple aspects of OA disease, aspects that could be assessed simultaneously at an in vivo system level.


Subject(s)
Bone Density/physiology , Cartilage, Articular/diagnostic imaging , Gait/physiology , Knee Joint/physiopathology , Osteoarthritis, Knee/physiopathology , Cartilage, Articular/metabolism , Humans , Osteoarthritis, Knee/diagnosis , Osteoarthritis, Knee/metabolism
5.
Osteoarthritis Cartilage ; 25(11): 1850-1857, 2017 11.
Article in English | MEDLINE | ID: mdl-28743608

ABSTRACT

OBJECTIVE: This study aimed to compare subchondral bone mineral density (sBMD) between non-radiographic osteoarthritic (OA) and medial femorotibial OA knees, using computed tomography (CT). DESIGN: CT exams from 16 non-radiographic OA (KL grade < 2) and 16 severe medial OA (KL grade ≥ 3) knees (average age of 61.7 ± 3 and 62.2 ± 5 years old respectively, 50% male in each group), were retrospectively analyzed. CT exams were segmented and 3D maps of sBMD based on the CT number in the most superficial 3 mm of femoral and tibial subchondral bone were computed. Average sBMD and medial-to-lateral sBMD ratios were calculated for total load-bearing regions and for sub-regions of interest in the femur and tibia. RESULTS: The analysis of total load-bearing regions did not reveal any significant difference between groups, except for the lateral tibia, where OA knees had lower sBMD. Sub-regional analysis unveiled differences with some sub-regions of the femur and tibia presenting significantly lower (in the lateral compartment) or higher (in the medial compartment) sBMD in OA knees compared to non-OA knees. The M/L sBMD ratios were significantly higher for OA knees compared to non-OA knees for all regions and sub-regions, except for the internal sub-regions. CONCLUSIONS: sBMD locally differs between non-OA and OA knees, in agreement with prior knowledge on biomechanics. CT proved to be a valuable tool for 3D analysis of femoral and tibial sBMD, which can be used in future studies to describe the chronology of sBMD alterations and improve our understanding of the role of subchondral bone in knee OA.


Subject(s)
Bone Density , Femur/diagnostic imaging , Knee Joint/diagnostic imaging , Osteoarthritis, Knee/diagnostic imaging , Tibia/diagnostic imaging , Aged , Arthrography , Case-Control Studies , Female , Humans , Image Processing, Computer-Assisted , Imaging, Three-Dimensional , Male , Middle Aged , Radiography , Retrospective Studies , Tomography, X-Ray Computed , Weight-Bearing
6.
Orthop Traumatol Surg Res ; 103(1): 21-25, 2017 02.
Article in English | MEDLINE | ID: mdl-27890581

ABSTRACT

BACKGROUND: Rates of dislocation following primary total hip arthroplasty (THA) vary from 0.5 to 10%. Dual-mobility cups in THA demonstrate increased stability. Clinical outcomes following THA with dual-mobility cups have been reported, but gait has not been assessed. Therefore we performed a retrospective case control study to answer: (1) is gait better in patients following THA with a dual-mobility cup than in frail, elderly patients of the same age? (2) Are clinical outcomes better in patients following THA with a dual-mobility cup than in frail, elderly patients? (3) What is the dislocation rate following THA with a dual-mobility cup? HYPOTHESIS: We hypothesized that patients who underwent THA with a dual-mobility cup have a better gait compared to frail, elderly patients of the same age. PATIENTS AND METHODS: Twenty patients (22 hips), mean age 79.9±7.7 (range, 62.3-88.3) years were assessed in this retrospective case-control series 5.6±1.4 (range: 4.1-8.8) years following dual-mobility cup THA. A reference group consisted of 72 "frail elderly" patients in a rehabilitation hospital for health problems unrelated to the lower limb, with no lower limb surgery or neurological conditions. Temporal and spatial gait performance were measured with four miniature gyroscopes, mounted on each thigh and calf, while patients walked freely along a 30m corridor. Harris Hip Score, WOMAC, radiological outcomes, and dislocation rate were determined. RESULTS: All gait parameters were better in the dual-mobility group compared to the frail elderly group. The dual-mobility group had a higher cadence (100.3 steps/minute versus 75.6 steps/minute), shorter (relative to gait cycle time) stance (61.6% versus 67.8%), shorter (relative to gait cycle time) double stance (23.3% versus 36.0%), longer stride (1.13m versus 0.80m), and faster walking speed (0.96m/s versus 0.52m/s). Range of motion of the shank, thigh and knee were better in the dual-mobility group. Harris Hip Score was 87.6±13.9 (range 51-100) and WOMAC score was 11.3±12.1 (range 0-34) in the THA group. We observed no dislocations. DISCUSSION: Gait patterns five years following THA with the dual-mobility cup were better or comparable to published study populations. LEVEL OF EVIDENCE: III, retrospective case-control series.


Subject(s)
Arthroplasty, Replacement, Hip/instrumentation , Gait , Hip Dislocation/etiology , Hip Joint/physiopathology , Hip Prosthesis , Aged , Aged, 80 and over , Arthroplasty, Replacement, Hip/adverse effects , Case-Control Studies , Female , Follow-Up Studies , Frail Elderly , Hip Prosthesis/adverse effects , Humans , Joint Instability/etiology , Knee Joint/physiopathology , Male , Middle Aged , Radiography , Range of Motion, Articular , Retrospective Studies , Treatment Outcome , Walking
7.
Bone Joint J ; 98-B(8): 1027-35, 2016 Aug.
Article in English | MEDLINE | ID: mdl-27482013

ABSTRACT

AIMS: Using a systematic review, we investigated whether there is an increased risk of post-operative infection in patients who have received an intra-articular corticosteroid injection to the hip for osteoarthritis prior to total hip arthroplasty (THA). METHODS: Studies dealing with an intra-articular corticosteroid injection to the hip and infection following subsequent THA were identified from databases for the period between 1990 to 2013. Retrieved articles were independently assessed for their methodological quality. RESULTS: A total of nine studies met the inclusion criteria. Two recommended against a steroid injection prior to THA and seven found no risk with an injection. No prospective controlled trials were identified. Most studies were retrospective. Lack of information about the methodology was a consistent flaw. CONCLUSIONS: The literature in this area is scarce and the evidence is weak. Most studies were retrospective, and confounding factors were poorly defined or not addressed. There is thus currently insufficient evidence to conclude that an intra-articular corticosteroid injection administered prior to THA increases the rate of infection. High quality, multicentre randomised trials are needed to address this issue. Cite this article: Bone Joint J 2016;98-B:1027-35.


Subject(s)
Adrenal Cortex Hormones/administration & dosage , Arthroplasty, Replacement, Hip/methods , Osteoarthritis, Hip/surgery , Surgical Wound Infection/etiology , Adrenal Cortex Hormones/adverse effects , Arthroplasty, Replacement, Hip/adverse effects , Escherichia coli Infections/chemically induced , Humans , Injections, Intra-Articular , Preoperative Care/adverse effects , Preoperative Care/methods , Staphylococcal Infections/chemically induced , Staphylococcus aureus , Streptococcal Infections/chemically induced
8.
Acta Biomater ; 21: 228-36, 2015 Jul.
Article in English | MEDLINE | ID: mdl-25797841

ABSTRACT

The present study was initiated with the aim to assess the in vivo electrochemical corrosion behaviour of CoCrMo biomedical alloys in human synovial fluids in an attempt to identify possible patient or pathology specific effects. For this, electrochemical measurements (open circuit potential OCP, polarization resistance Rp, potentiodynamic polarization curves, electrochemical impedance spectroscopy EIS) were carried out on fluids extracted from patients with different articular pathologies and prosthesis revisions. Those electrochemical measurements could be carried out with outstanding precision and signal stability. The results show that the corrosion behaviour of CoCrMo alloy in synovial fluids not only depends on material reactivity but also on the specific reactions of synovial fluid components, most likely involving reactive oxygen species. In some patients the latter were found to determine the whole cathodic and anodic electrochemical response. Depending on patients, corrosion rates varied significantly between 50 and 750 mg dm(-2)year(-1).


Subject(s)
Alloys/metabolism , Corrosion , Electrochemical Techniques , Synovial Fluid/chemistry , Chromium/chemistry , Cobalt/chemistry , Humans , Molybdenum/chemistry
9.
Physiol Meas ; 36(3): 547-60, 2015 Mar.
Article in English | MEDLINE | ID: mdl-25690269

ABSTRACT

Kinematic functional evaluation with body-worn sensors provides discriminative and responsive scores after shoulder surgery, but the optimal movements' combination has not yet been scientifically investigated. The aim of this study was the development of a simplified shoulder function kinematic score including only essential movements. The P Score, a seven-movement kinematic score developed on 31 healthy participants and 35 patients before surgery and at 3, 6 and 12 months after shoulder surgery, served as a reference. Principal component analysis and multiple regression were used to create simplified scoring models. The candidate models were compared to the reference score. ROC curve for shoulder pathology detection and correlations with clinical questionnaires were calculated. The B-B Score (hand to the Back and hand upwards as to change a Bulb) showed no difference to the P Score in time*score interaction (P > .05) and its relation with the reference score was highly linear (R(2) > .97). Absolute value of correlations with clinical questionnaires ranged from 0.51 to 0.77. Sensitivity was 97% and specificity 94%. The B-B and reference scores are equivalent for the measurement of group responses. The validated simplified scoring model presents practical advantages that facilitate the objective evaluation of shoulder function in clinical practice.


Subject(s)
Movement/physiology , Physical Examination/methods , Severity of Illness Index , Shoulder/physiology , Shoulder/physiopathology , Adult , Biomechanical Phenomena , Female , Humans , Humerus/physiology , Humerus/physiopathology , Male , Middle Aged , Principal Component Analysis , Regression Analysis , Shoulder/surgery , Surveys and Questionnaires , Time Factors , Treatment Outcome
10.
Med Eng Phys ; 36(6): 721-5, 2014 Jun.
Article in English | MEDLINE | ID: mdl-24405737

ABSTRACT

Ligament balance is an important and subjective task performed during total knee arthroplasty (TKA) procedure. For this reason, it is desirable to develop instruments to quantitatively assess the soft-tissue balance since excessive imbalance can accelerate prosthesis wear and lead to early surgical revision. The instrumented distractor proposed in this study can assist surgeons on performing ligament balance by measuring the distraction gap and applied load. Also the device allows the determination of the ligament stiffness which can contribute a better understanding of the intrinsic mechanical behavior of the knee joint. Instrumentation of the device involved the use of hall-sensors for measuring the distractor displacement and strain gauges to transduce the force. The sensors were calibrated and tested to demonstrate their suitability for surgical use. Results show the distraction gap can be measured reliably with 0.1mm accuracy and the distractive loads could be assessed with an accuracy in the range of 4N. These characteristics are consistent with those have been proposed, in this work, for a device that could assist on performing ligament balance while permitting surgeons evaluation based on his experience. Preliminary results from in vitro tests were in accordance with expected stiffness values for medial collateral ligament (MCL) and lateral collateral ligament (LCL).


Subject(s)
Arthroplasty, Replacement, Knee/instrumentation , Elasticity , Knee Joint/physiopathology , Knee Joint/surgery , Ligaments/physiopathology , Ligaments/surgery , Arthroplasty, Replacement, Knee/methods , Biomechanical Phenomena , Calibration , Collateral Ligaments/physiopathology , Equipment Design , Femur , Humans , Intraoperative Period , Medial Collateral Ligament, Knee/physiopathology , Movement/physiology , Reproducibility of Results , Tibia
11.
Knee Surg Sports Traumatol Arthrosc ; 22(7): 1556-62, 2014 Jul.
Article in English | MEDLINE | ID: mdl-23771349

ABSTRACT

PURPOSE: Reconstruction of the posterior cruciate ligament (PCL) yields less satisfying results than anterior cruciate ligament reconstruction with respect to laxity control. Accurate tibial tunnel placement is crucial for successful PCL reconstruction using arthroscopic tibial tunnel techniques. A discrepancy between anatomical studies of the tibial PCL insertion site and surgical recommendations for tibial tunnel placement remains. The objective of this study was to identify the optimal placement of the tibial tunnel in PCL reconstruction based on clinical studies. METHODS: In a systematic review of the literature, MEDLINE, EMBASE, Cochrane Review, and Cochrane Central Register of Controlled Trials were screened for articles about PCL reconstruction from January 1990 to September 2011. Clinical trials comparing at least two PCL reconstruction techniques were extracted and independently analysed by each author. Only studies comparing different tibial tunnel placements in the retrospinal area were included. RESULTS: This systematic review found no comparative clinical trial for tibial tunnel placement in PCL reconstruction. Several anatomical, radiological, and biomechanical studies have described the tibial insertion sites of the native PCL and have led to recommendations for placement of the tibial tunnel outlet in the retrospinal area. However, surgical recommendations and the results of morphological studies are often contradictory. CONCLUSIONS: Reliable anatomical landmarks for tunnel placement are lacking. Future randomized controlled trials could compare precisely defined tibial tunnel placements in PCL reconstruction, which would require an established mapping of the retrospinal area of the tibial plateau with defined anatomical and radiological landmarks.


Subject(s)
Osteotomy/methods , Plastic Surgery Procedures/methods , Posterior Cruciate Ligament/injuries , Posterior Cruciate Ligament/surgery , Tibia/anatomy & histology , Tibia/surgery , Humans
12.
Article in English | MEDLINE | ID: mdl-22978618

ABSTRACT

Bone defects in revision knee arthroplasty are often located in load-bearing regions. The goal of this study was to determine whether a physiologic load could be used as an in situ osteogenic signal to the scaffolds filling the bone defects. In order to answer this question, we proposed a novel translation procedure having four steps: (1) determining the mechanical stimulus using finite element method, (2) designing an animal study to measure bone formation spatially and temporally using micro-CT imaging in the scaffold subjected to the estimated mechanical stimulus, (3) identifying bone formation parameters for the loaded and non-loaded cases appearing in a recently developed mathematical model for bone formation in the scaffold and (4) estimating the stiffness and the bone formation in the bone-scaffold construct. With this procedure, we estimated that after 3 years mechanical stimulation increases the bone volume fraction and the stiffness of scaffold by 1.5- and 2.7-fold, respectively, compared to a non-loaded situation.


Subject(s)
Arthroplasty, Replacement, Knee , Osteogenesis , Animals , Bone and Bones/diagnostic imaging , Bone and Bones/physiology , Finite Element Analysis , Models, Biological , Rats , Tissue Engineering , Tissue Scaffolds , Weight-Bearing/physiology , X-Ray Microtomography
13.
J Biomech ; 45(11): 2041-5, 2012 Jul 26.
Article in English | MEDLINE | ID: mdl-22695637

ABSTRACT

The joint angles of multi-segment foot models have been primarily described using two mathematical methods: the joint coordinate system and the attitude vector. This study aimed to determine whether the angles obtained through these two descriptors are comparable, and whether these descriptors have similar sensitivity to experimental errors. Six subjects walked eight times on an instrumented walkway while the joint angles among shank, hindfoot, medial forefoot, and lateral forefoot were measured. The angles obtained using both descriptors and their sensitivity to experimental errors were compared. There was no overall significant difference between the ranges of motion obtained using both descriptors. However, median differences of more than 6° were noticed for the medial-lateral forefoot joint. For all joints and rotation planes, both descriptors provided highly similar angle patterns (median correlation coefficient: R>0.90), except for the medial-lateral forefoot angle in the transverse plane (median R=0.77). The joint coordinate system was significantly more sensitive to anatomical landmarks misplacement errors. However, the absolute differences of sensitivity were small relative to the joints ranges of motion. In conclusion, the angles obtained using these two descriptors were not identical, but were similar for at least the shank-hindfoot and hindfoot-medial forefoot joints. Therefore, the angle comparison across descriptors is possible for these two joints. Comparison should be done more carefully for the medial-lateral forefoot joint. Moreover, despite different sensitivities to experimental errors, the effects of the experimental errors on the angles were small for both descriptors suggesting that both descriptors can be considered for multi-segment foot models.


Subject(s)
Foot Joints/anatomy & histology , Foot Joints/physiology , Imaging, Three-Dimensional/methods , Models, Anatomic , Models, Biological , Range of Motion, Articular/physiology , Walking/physiology , Adult , Computer Simulation , Female , Humans , Male , Reproducibility of Results , Sensitivity and Specificity
14.
J Bone Joint Surg Br ; 94(5): 648-55, 2012 May.
Article in English | MEDLINE | ID: mdl-22529085

ABSTRACT

This study compared the outcome of total knee replacement (TKR) in adult patients with fixed- and mobile-bearing prostheses during the first post-operative year and at five years' follow-up, using gait parameters as a new objective measure. This double-blind randomised controlled clinical trial included 55 patients with mobile-bearing (n = 26) and fixed-bearing (n = 29) prostheses of the same design, evaluated pre-operatively and post-operatively at six weeks, three months, six months, one year and five years. Each participant undertook two walking trials of 30 m and completed the EuroQol questionnaire, Western Ontario and McMaster Universities osteoarthritis index, Knee Society score, and visual analogue scales for pain and stiffness. Gait analysis was performed using five miniature angular rate sensors mounted on the trunk (sacrum), each thigh and calf. The study population was divided into two groups according to age (≤ 70 years versus > 70 years). Improvements in most gait parameters at five years' follow-up were greater for fixed-bearing TKRs in older patients (> 70 years), and greater for mobile-bearing TKRs in younger patients (≤ 70 years). These findings should be confirmed by an extended age controlled study, as the ideal choice of prosthesis might depend on the age of the patient at the time of surgery.


Subject(s)
Arthroplasty, Replacement, Knee/instrumentation , Gait , Knee Prosthesis , Osteoarthritis, Knee/surgery , Age Factors , Aged , Arthroplasty, Replacement, Knee/adverse effects , Arthroplasty, Replacement, Knee/methods , Arthroplasty, Replacement, Knee/rehabilitation , Double-Blind Method , Female , Humans , Knee Joint/physiopathology , Male , Middle Aged , Osteoarthritis, Knee/physiopathology , Osteoarthritis, Knee/rehabilitation , Pain Measurement/methods , Prosthesis Design , Quality of Life , Range of Motion, Articular , Recovery of Function , Treatment Outcome
15.
J Biomech ; 43(11): 2196-202, 2010 Aug 10.
Article in English | MEDLINE | ID: mdl-20483415

ABSTRACT

Thanks to decades of research, gait analysis has become an efficient tool. However, mainly due to the price of the motion capture systems, standard gait laboratories have the capability to measure only a few consecutive steps of ground walking. Recently, wearable systems were proposed to measure human motion without volume limitation. Although accurate, these systems are incompatible with most of existing calibration procedures and several years of research will be necessary for their validation. A new approach consisting of using a stationary system with a small capture volume for the calibration procedure and then to measure gait using a wearable system could be very advantageous. It could benefit from the knowledge related to stationary systems, allow long distance monitoring and provide new descriptive parameters. The aim of this study was to demonstrate the potential of this approach. Thus, a combined system was proposed to measure the 3D lower body joints angles and segmental angular velocities. It was then assessed in terms of reliability towards the calibration procedure, repeatability and concurrent validity. The dispersion of the joint angles across calibrations was comparable to those of stationary systems and good reliability was obtained for the angular velocities. The repeatability results confirmed that mean cycle kinematics of long distance walks could be used for subjects' comparison and pointed out an interest for the variability between cycles. Finally, kinematics differences were observed between participants with different ankle conditions. In conclusion, this study demonstrated the potential of a mixed approach for human movement analysis.


Subject(s)
Acceleration , Algorithms , Gait/physiology , Locomotion/physiology , Magnetics/instrumentation , Monitoring, Ambulatory/instrumentation , Adult , Clothing , Equipment Design , Equipment Failure Analysis , Female , Humans , Male
16.
J Biomech ; 42(14): 2330-5, 2009 Oct 16.
Article in English | MEDLINE | ID: mdl-19665712

ABSTRACT

Measurement of three-dimensional (3D) knee joint angle outside a laboratory is of benefit in clinical examination and therapeutic treatment comparison. Although several motion capture devices exist, there is a need for an ambulatory system that could be used in routine practice. Up-to-date, inertial measurement units (IMUs) have proven to be suitable for unconstrained measurement of knee joint differential orientation. Nevertheless, this differential orientation should be converted into three reliable and clinically interpretable angles. Thus, the aim of this study was to propose a new calibration procedure adapted for the joint coordinate system (JCS), which required only IMUs data. The repeatability of the calibration procedure, as well as the errors in the measurement of 3D knee angle during gait in comparison to a reference system were assessed on eight healthy subjects. The new procedure relying on active and passive movements reported a high repeatability of the mean values (offset<1 degrees) and angular patterns (SD<0.3 degrees and CMC>0.9). In comparison to the reference system, this functional procedure showed high precision (SD<2 degrees and CC>0.75) and moderate accuracy (between 4.0 degrees and 8.1 degrees) for the three knee angle. The combination of the inertial-based system with the functional calibration procedure proposed here resulted in a promising tool for the measurement of 3D knee joint angle. Moreover, this method could be adapted to measure other complex joint, such as ankle or elbow.


Subject(s)
Acceleration , Imaging, Three-Dimensional/instrumentation , Knee Joint/anatomy & histology , Knee Joint/physiology , Monitoring, Ambulatory/instrumentation , Range of Motion, Articular/physiology , Transducers , Adult , Calibration , Equipment Design , Equipment Failure Analysis , Female , Humans , Male , Reproducibility of Results , Sensitivity and Specificity , Walking/physiology , Young Adult
17.
Orthop Traumatol Surg Res ; 95(2): 89-99, 2009 Apr.
Article in English | MEDLINE | ID: mdl-19345630

ABSTRACT

BACKGROUND: An objective measurement of surgical procedures outcomes is inherent to professional practices quality control; this especially applies in orthopaedics to joint replacement outcomes. A self-administered questionnaire offers an attractive alternative to surgeon's judgement but is infrequently used in France for these purposes. The British questionnaire, the 12-item Oxford Hip Score (OHS) was selected for this study because of its ease of use. HYPOTHESIS: The objective of this study was to validate the French translation of the self-assessment 12-item Oxford Hip Score and compare its results with those of the reference functional scores: the Harris Hip Score (HHS) and the Postel-Merle d'Aubigné (PMA) score. MATERIALS AND METHODS: Based on a clinical series of 242 patients who were candidates for total hip arthroplasty, the French translation of this questionnaire was validated. Its coherence was also validated by comparing the preoperative data with the data obtained from the two other reference clinical scores. RESULTS: The translation was validated using the forward-backward translation procedure from French to English, with correction of all differences or mistranslations after systematized comparison with the original questionnaire in English. The mean overall OHS score was 43.8 points (range, 22-60 points) with similarly good distribution of the overall value of the three scores compared. The correlation was excellent between the OHS and the HHS, but an identical correlation between the OHS and the PMA was only obtained for the association of the pain and function parameters, after excluding the mobility criterion, relatively over-represented in the PMA score. DISCUSSION AND CONCLUSION: Subjective questionnaires that contribute a personal appreciation of the results of arthroplasty by the patient can easily be applied on a large scale. This study made a translated and validated version of an internationally recognized, reliable self-assessment score available to French orthopaedic surgeons. The results obtained encourage us to use this questionnaire as a complement to the classical evaluation scores and methods.


Subject(s)
Arthroplasty, Replacement, Hip/standards , Cross-Cultural Comparison , Range of Motion, Articular/physiology , Sickness Impact Profile , Surveys and Questionnaires , Activities of Daily Living , Arthroplasty, Replacement, Hip/adverse effects , Disability Evaluation , Female , France , Hip Prosthesis , Humans , Linear Models , Male , Orthopedics/standards , Pain, Postoperative/physiopathology , Practice Patterns, Physicians' , Probability , Sensitivity and Specificity , United Kingdom
18.
Int Orthop ; 33(1): 27-33, 2009 Feb.
Article in English | MEDLINE | ID: mdl-17717664

ABSTRACT

Freehand positioning of the femoral drill guide is difficult during hip resurfacing and the surgeon is often unsure of the implant position achieved peroperatively. The purpose of this study was to find out whether, by using a navigation system, acetabular and femoral component positioning could be made easier and more precise. Eighteen patients operated on by the same surgeon were matched by sex, age, BMI, diagnosis and ASA score (nine patients with computer assistance, nine with the regular ancillary). Pre-operative planning was done on standard AP and axial radiographs with CT scan views for the computer-assisted operations. The final position of implants was evaluated by the same radiographs for all patients. The follow-up was at least 1 year. No difference between both groups in terms of femoral component position was observed (p > 0.05). There was also no difference in femoral notching. A trend for a better cup position was observed for the navigated hips, especially for cup anteversion. There was no additional operating time for the navigated hips. Hip navigation for resurfacing surgery may allow improved visualisation and hip implant positioning, but its advantage probably will be more obvious with mini-incisions than with regular incision surgery.


Subject(s)
Arthroplasty, Replacement, Hip/methods , Arthroplasty, Replacement, Hip/standards , Metals , Surgery, Computer-Assisted/methods , Surgery, Computer-Assisted/standards , Adult , Arthroplasty, Replacement, Hip/adverse effects , Body Mass Index , Female , Follow-Up Studies , Hip Joint/diagnostic imaging , Hip Joint/surgery , Humans , Male , Middle Aged , Tomography, X-Ray Computed , Treatment Outcome
19.
J Biomech ; 41(5): 1029-35, 2008.
Article in English | MEDLINE | ID: mdl-18222459

ABSTRACT

Three-dimensional measurement of joint motion is a promising tool for clinical evaluation and therapeutic treatment comparisons. Although many devices exist for joints kinematics assessment, there is a need for a system that could be used in routine practice. Such a system should be accurate, ambulatory, and easy to use. The combination of gyroscopes and accelerometers (i.e., inertial measurement unit) has proven to be suitable for unrestrained measurement of orientation during a short period of time (i.e., few minutes). However, due to their inability to detect horizontal reference, inertial-based systems generally fail to measure differential orientation, a prerequisite for computing the three-dimentional knee joint angle recommended by the Internal Society of Biomechanics (ISB). A simple method based on a leg movement is proposed here to align two inertial measurement units fixed on the thigh and shank segments. Based on the combination of the former alignment and a fusion algorithm, the three-dimensional knee joint angle is measured and compared with a magnetic motion capture system during walking. The proposed system is suitable to measure the absolute knee flexion/extension and abduction/adduction angles with mean (SD) offset errors of -1 degree (1 degree ) and 0 degrees (0.6 degrees ) and mean (SD) root mean square (RMS) errors of 1.5 degrees (0.4 degrees ) and 1.7 degrees (0.5 degrees ). The system is also suitable for the relative measurement of knee internal/external rotation (mean (SD) offset error of 3.4 degrees (2.7 degrees )) with a mean (SD) RMS error of 1.6 degrees (0.5 degrees ). The method described in this paper can be easily adapted in order to measure other joint angular displacements such as elbow or ankle.


Subject(s)
Knee Joint/physiology , Monitoring, Ambulatory/methods , Adult , Hip Joint/physiology , Humans , Male , Posture/physiology , Range of Motion, Articular/physiology , Walking/physiology
20.
Ann R Coll Surg Engl ; 89(3): 259-61, 2007 Apr.
Article in English | MEDLINE | ID: mdl-17394710

ABSTRACT

INTRODUCTION: Extensor mechanism ruptures might be easily overlooked and misdiagnosed, and delayed diagnosis of quadriceps tendon rupture is frequent. However, the literature recommends early surgical repair within 72 h. PATIENTS AND METHODS: This paper describes a new simple clinical diagnostic test that directly evaluates the integrity of the distal 5 cm of the quadriceps tendon itself. It consists of inserting a needle in the tendon, proximal to the suspected rupture and mobilising the knee joint. RESULTS: The suspected ruptured quadriceps tendons with a positive 'needle' diagnostic test were confirmed intra-operatively. CONCLUSIONS: This minimally invasive and easily available technique should be considered in the diagnostic work-up and treatment planning of patients with suspected tears of the quadriceps tendon.


Subject(s)
Needles , Physical Examination/standards , Quadriceps Muscle/injuries , Tendon Injuries/diagnosis , Humans , Rupture/diagnosis , Sensitivity and Specificity
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