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1.
Sci Rep ; 13(1): 22287, 2023 12 15.
Article in English | MEDLINE | ID: mdl-38097696

ABSTRACT

One major issue in pharmaceutical supply chain management is the supply shortage, and determining the root causes of medicine shortages necessitates an in-depth investigation. The concept of risk management is proposed in this study to identify significant risk factors in the pharmaceutical supply chain. Fuzzy failure mode and effect analysis and data envelopment analysis were used to evaluate the risks of the pharmaceutical supply chain. Based on a case study on the Malaysian pharmaceutical supply chain, it reveals that the pharmacy node is the riskiest link. The unavailability of medicine due to unexpected demand, as well as the scarcity of specialty or substitute drugs, pose the most significant risk factors. These risks could be mitigated by digital technology. We propose an appropriate digital technology platform consisting of big data analytics and blockchain technologies to undertake these challenges of supply shortage. By addressing risk factors through the implementation of a digitalized supply chain, organizations can fortify their supply networks, fostering resilience and efficiency, and thereby playing a pivotal role in advancing the Pharma 4.0 era.


Subject(s)
Blockchain , Pharmaceutical Preparations , Pharmacy , Pharmaceutical Preparations/supply & distribution , Risk Management
2.
Comput Econ ; : 1-52, 2023 Feb 01.
Article in English | MEDLINE | ID: mdl-36747892

ABSTRACT

In this work, a machine learning application was constructed to predict the logistics performance index based on economic attributes. The prediction procedure employs both linear and non-linear machine learning algorithms. The macroeconomic panel dataset is used in this investigation. Furthermore, it was combined with the microeconomic panel dataset obtained through the data envelopment analysis method for evaluating financial efficiency. The procedure was implemented in six ASEAN member countries. The non-linear algorithm of an artificial neural network performed best on the complex pattern of a collective instance of these six countries, followed by the penalized linear of the Ridge regression method. Due to the limited amount of training data for each country, the artificial neural network prediction procedure is only applicable to the datasets of Singapore, Malaysia, and the Philippines. Ridge regression fits the Indonesia, Thailand and Vietnam datasets. The results provide precise trend forecasting. Macroeconomic factors are driving up the logistics performance index in Vietnam in 2020. Malaysia logistics performance is influenced by the logistics business's financial efficiency. The results at the country level can be used to track, improve, and reform the country's short-term logistics and supply chain policies. This can bring significant gains in national logistics and supply chain capabilities, as well as support for global trade collaboration, all for the long-term development of the region.

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