ABSTRACT
The antimicrobial action of 11 compounds involving guaiacyl- and syringyl-like structures (low-molecular-weight part of lignin), gallic acid and its derivatives, cinnamic acid and its derivatives, veratric acid, anisic acid and crotonic acid (a total of 25 compounds) against bacteria, yeast-like organisms and protozoa was examined. Aromatic compounds modified in the C-side chain and aldehydes were effective preferentially against Trichomonas vaginalis, whereas against bacteria and yeast-like organisms eugenol was the most effective inhibitor.
Subject(s)
Anti-Infective Agents , Plants, Medicinal , Polycyclic Compounds/isolation & purification , Anti-Bacterial Agents , Microbial Sensitivity Tests , Polycyclic Compounds/pharmacology , Pseudomonas aeruginosa/drug effects , Staphylococcus aureus/drug effects , Trichosporon/drug effectsABSTRACT
Inhibitory effects of compounds with guaiacyl and syringyl structure, representing the structure of native lignin, were studied on model cultures of bacteria, yeasts, yeast-like microorganisms and moulds. Isoeugenol exhibited the most pronounced inhibitory effect on growth of the studied microorganisms.
