Subject(s)
Fistula/diagnosis , Lacrimal Apparatus Diseases/diagnosis , Adult , Aged, 80 and over , Female , Fistula/congenital , Fistula/surgery , Humans , Lacrimal Apparatus Diseases/congenital , Lacrimal Apparatus Diseases/surgery , Lacrimal Duct Obstruction/diagnosis , Male , Middle Aged , Ophthalmologic Surgical Procedures , Retrospective StudiesSubject(s)
Eyelid Diseases/drug therapy , Glucocorticoids/therapeutic use , Graves Ophthalmopathy/drug therapy , Oculomotor Muscles/drug effects , Triamcinolone Acetonide/therapeutic use , Adult , Eyelid Diseases/physiopathology , Female , Graves Ophthalmopathy/physiopathology , Humans , Injections, Intramuscular , Magnetic Resonance Imaging , Oculomotor Muscles/physiopathology , Young AdultABSTRACT
The aim of this study was to describe a modified technique of intraorbital irrigation of amphotericin B in the treatment of rhino-orbital mucormycosis. A 38-year-old man was diagnosed with rhino-orbital mucormycosis and subsequently underwent orbital and sinus debridement with postoperative intraorbital irrigation of amphotericin B. Daily irrigation of amphotericin B was infused in the orbit with measures taken to avoid iatrogenic toxicity to the ocular surface and gastrointestinal tract. The use of local amphotericin B irrigation directly in the orbit allowed for local control of infection without orbital exenteration, a good cosmetic outcome and excellent postoperative visual acuity. The published reports on the use of intraorbital irrigation with amphotericin B in mucormycosis infections were reviewed and the technique used at the institution was outlined.
Subject(s)
Amphotericin B/administration & dosage , Antifungal Agents/administration & dosage , Eye Infections, Fungal/therapy , Mucormycosis/therapy , Paranasal Sinus Diseases/therapy , Adult , Drainage/methods , Humans , Male , Ophthalmologic Surgical Procedures/methods , Orbit/surgery , Therapeutic Irrigation , Treatment OutcomeABSTRACT
The authors report a case of a 72-year-old woman with unilateral, complete, reversible blindness (no light perception) immediately after uncomplicated repair of an orbital floor fracture. In this case, vision loss was reversed with prompt surgical intervention with removal of the orbital floor implant. The authors review the etiology of vision loss after orbital fracture repair and hypothesize as to the cause of blindness in this case. Given the frequency with which orbital fracture repair is performed by a variety of surgical subspecialists, it is imperative for surgeons to be familiar with the ophthalmic complications and be aware of the multiple causes of postoperative vision loss. The authors propose that immediate postoperative assessment of visual function be performed on all patients undergoing orbital fracture repair.
Subject(s)
Blindness/etiology , Orbital Fractures/surgery , Orbital Implants/adverse effects , Postoperative Complications , Recovery of Function , Visual Acuity/physiology , Aged , Blindness/physiopathology , Female , HumansABSTRACT
The human tear film is a 3-layered coating of the surface of the eye and a loss, or reduction, in any layer of this film may result in a syndrome of blurry vision and burning pain of the eyes known as dry eye. The lacrimal gland and accessory glands provide multiple components to the tear film, most notably the aqueous. Dysfunction of these glands results in the loss of aqueous and other products required in ocular surface maintenance and health resulting in dry eye and the potential for significant surface pathology. In this paper, we have reviewed products of the lacrimal gland, diseases known to affect the gland, and historical and emerging dry eye therapies targeting lacrimal gland dysfunction.
Subject(s)
Emphysema/diagnosis , Eye Foreign Bodies/diagnosis , Eye Injuries, Penetrating/diagnosis , Orbit/injuries , Orbital Diseases/diagnosis , Polystyrenes , Child, Preschool , Diagnosis, Differential , Eye Foreign Bodies/surgery , Eye Injuries, Penetrating/surgery , Female , Humans , Orbital Diseases/surgery , Tomography, X-Ray ComputedABSTRACT
We present the magnetic resonance imaging findings of posterior ischemic optic neuropathy in a patient with posterior reversible encephalopathy syndrome secondary to hypertensive emergency.
Subject(s)
Hypertension/complications , Optic Neuropathy, Ischemic/complications , Adult , Brain/pathology , Female , Humans , Hypertension/diagnosis , Magnetic Resonance Imaging , Optic Nerve/pathology , Optic Neuropathy, Ischemic/diagnosis , Posterior Leukoencephalopathy Syndrome/diagnosisABSTRACT
BACKGROUND: The use of dispersive ophthalmic viscosurgical devices (OVDs) has been shown to provide significant protection against air bubble damage to the corneal endothelium when compared with cohesive OVDs. We compared the corneal endothelial protective effects of a new dispersive OVD, Healon-D, with Viscoat. METHODS: Healon-D and Viscoat were used in a randomized and masked fashion in the anterior chamber of 40 rabbit eyes during a procedure where ultrasound at 70% continuous energy was delivered for 2 min. Two millilitres of air bubbles were injected into the anterior chamber during the first minute of the procedure on each eye. Corneas were then stained with trypan blue and alizarin red and evaluated via light microscopy for endothelial injury. Both denuding of the endothelial layer, as well as damage to endothelial cells were quantified by using the Evaluation of Posterior Capsule Opacification digital imaging system. RESULTS: The denuded area for eyes treated with Healon-D and Viscoat were not significantly different (medians of 0.004167and 0.003333, respectively, P = 0.8908). There was no significant difference in the area of endothelial cell damaged (medians of 0.02183 and 0.01433, respectively, P = 0.4565). When the denuded and damaged areas were calculated together, there was also no difference in the total injured area (medians of 0.05817 and 0.05821, respectively, P = 0.5740). CONCLUSION: The new dispersive OVD Healon-D is equally as effective as Viscoat in protecting the corneal endothelial layer from denuding and damage from air bubbles during anterior segment surgery.
