Subject(s)
Ethambutol/therapeutic use , Rifampin/therapeutic use , Tuberculosis, Pulmonary/drug therapy , Drug Hypersensitivity , Drug Resistance, Microbial , Ethambutol/adverse effects , Humans , Mycobacterium tuberculosis/drug effects , Recurrence , Rifampin/adverse effects , Time Factors , Tuberculosis, Pulmonary/microbiology , Tuberculosis, Pulmonary/rehabilitationABSTRACT
Of the 118 patients suffering from chronic pulmonary tuberculosis, living within the district of the Tîrgu Mures Tuberculosis Dispensary, 100 accepted a strictly surveyed treatment and of these 90 continued for at least 6 months. The present paper reports on the immediate radiologic and bacteriological results and the factors influencing them. The following conclusions were drawn: 1) A 2/7 Rifampicin/Etambutol strictly supervised treatment is the most efficient method for neutralizing chronic bacillary sources. 2) The age and origin of the patients, the duration and extent of the pulmonary process, duration of the treatment and associated diseases are the factors that furnish the prognosis of the expected results. 3) Apart from the very good results obtained the method cannot solve all chronic cases and the classical antiepidemic measures must be applied in continuation.