Impact of memory load on processing diminishes rapidly during retention in a complex span paradigm.

Previous work with complex memory span tasks, in which simple choice decisions are imposed between presentations of to-be-remembered items, shows that these secondary tasks reduce memory span. It is less clear how reconfiguring and maintaining various amounts of information affects decision speeds. We introduced preliminary "lead-in" decisions and postencoding "lead-out" decisions to isolate potential influences of reconfiguration and maintenance on decision speeds. Compared with preliminary lead-in choice responses, the response associated with the first memory item slowed substantially. As the list accumulated, decision responses slowed even more. After presentation of the list was complete, decision responses sped rapidly: within a few seconds, decisions were at least as fast as when remembering a single item. These patterns appeared consistently regardless of differences in list length (4, 5, 6, or 7 to-be-remembered items) and response mode (spoken, selection via mouse). This pattern of findings is inconsistent with the idea that merely holding information in mind conflicts with attention-demanding decision tasks. Instead, it is likely that reconfiguring memory items for responding is the source of conflict between memory and processing in complex span tasks. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Lexical access speed and the development of phonological recoding during immediate serial recall.

A recent Registered Replication Report (RRR) of the development of verbal rehearsal during serial recall (Elliott et al., 2021) revealed that children verbalized at younger ages than previously thought (Flavell et al., 1966), but did not identify sources of individual differences. Here we use mediation analysis to reanalyze data from the 934 children ranging from 5 to 10 years old from the RRR for that purpose. From ages 5 to 7, the time taken for a child to label pictures (i.e. isolated naming speed) predicted the child's spontaneous use of labels during a visually-presented serial reconstruction task, despite no need for spoken responses. For 6- and 7-year-olds, isolated naming speed also predicted recall. The degree to which verbalization mediated the relation between isolated naming speed and recall changed across development. All relations dissipated by age 10. The same general pattern was observed in an exploratory analysis of delayed recall for which greater demands are placed on rehearsal for item maintenance. Overall, our findings suggest that spontaneous phonological recoding during a standard short-term memory task emerges around age 5, increases in efficiency during the early elementary school years, and is sufficiently automatic by age 10 to support immediate serial recall in most children. Moreover, the findings highlight the need to distinguish between phonological recoding and rehearsal in developmental studies of short-term memory.

Factors associated with homelessness among women: a cross-sectional survey of outpatient mental health service users at The Banyan, India.

BACKGROUND: Homelessness has multifaceted and damaging effects on women with mental illness. This makes it imperative to identify and address the factors leading to homelessness among women with mental illness in order to inform policy on providing relevant services for this vulnerable population. METHOD: A cross-sectional survey was conducted among 346 women in active contact with one of four outpatient clinics at The Banyan, a non-profit organization in the Indian state of Tamil Nadu. A semi-structured instrument and modified version of the List of Threatening Experiences Questionnaire was used for data collection. Multivariate logistic regression analysis was used to examine predictive variables for homelessness among women with mental illness. RESULT: 32.65% of participants reported a history of homelessness. Less than 5 years of schooling (OR = 2.914, 95% CI = 1.027-8.269, P < 0.05) and disrupted relationships (OR = 1.807, 95% CI = 1.23-2.655, P < 0.01) were associated with a greater likelihood of women with mental illness to experience homelessness. CONCLUSION: In the study cohort, this was explained mainly by factors rooted in gender-based disadvantage. Further practice and research are needed to develop interventions that address issues with a sociological basis to mental illness and prevent these predictive factors.

Efficacy of Low-Carbohydrate Ketogenic Diet as an Adjuvant Cancer Therapy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

BACKGROUND: The role of low-carbohydrate ketogenic diet (LCKD) as an adjuvant therapy in antitumor treatment is not well established. This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to investigate the efficacy of LCKD as an adjuvant therapy in antitumor treatment compared to non-ketogenic diet in terms of lipid profile, body weight, fasting glucose level, insulin, and adverse effects; Methods: In this study, databases such as PubMed, Web of Science, Scopus, CINAHL, and Cochrane trials were searched. Only RCTs that involved cancer participants that were assigned to dietary interventions including a LCKD group and a control group (any non-ketogenic dietary intervention) were selected. Three reviewers independently extracted the data, and the meta-analysis was performed using a fixed effects model or random effects model depending on the I2 value or p-value; Results: A total of six articles met the inclusion/exclusion criteria. In the overall analysis, the post-intervention results = standard mean difference, SMD (95% CI) showed total cholesterol (TC) level = 0.25 (-0.17, 0.67), HDL-cholesterol = -0.07 (-0.50, 0.35), LDL-cholesterol = 0.21 (-0.21, 0.63), triglyceride (TG) = 0.09 (-0.33, 0.51), body weight (BW) = -0.34 (-1.33, 0.65), fasting blood glucose (FBG) = -0.40 (-1.23, 0.42) and insulin = 0.11 (-1.33, 1.55). There were three outcomes showing significant results in those in LCKD group: the tumor marker PSA, p = 0.03, the achievement of ketosis p = 0.010, and the level of satisfaction, p = 0.005; Conclusions: There was inadequate evidence to support the beneficial effects of LCKDs on antitumor therapy. More trials comparing LCKD and non-KD with a larger sample size are necessary to give a more conclusive result.

Effects of dairy products, calcium and vitamin D on ovarian cancer risk: a meta-analysis of twenty-nine epidemiological studies.

Findings for the roles of dairy products, Ca and vitamin D on ovarian cancer risk remain controversial. We aimed to assess these associations by using an updated meta-analysis. Five electronic databases (e.g. PubMed and Embase) were searched from inception to 24 December 2019. Pooled relative risks (RR) with 95 % CI were calculated. A total of twenty-nine case-control or cohort studies were included. For comparisons of the highest v. lowest intakes, higher whole milk intake was associated with increased ovarian cancer risk (RR 1·35; 95 % CI 1·15, 1·59), whereas decreased risks were observed for higher intakes of low-fat milk (RR 0·84; 95 % CI 0·73, 0·96), dietary Ca (RR 0·71; 95 % CI 0·60, 0·84) and dietary vitamin D (RR 0·80; 95 % CI 0·67, 0·95). Additionally, for every 100 g/d increment, increased ovarian cancer risks were found for total dairy products (RR 1·03; 95 % CI 1·01, 1·04) and for whole milk (RR 1·07; 95 % CI 1·03, 1·11); however, decreased risks were found for 100 g/d increased intakes of low-fat milk (RR 0·95; 95 % CI 0·91, 0·99), cheese (RR 0·87; 95 % CI 0·76, 0·98), dietary Ca (RR 0·96; 95 % CI 0·95, 0·98), total Ca (RR 0·98; 95 % CI 0·97, 0·99), dietary vitamin D (RR 0·92; 95 % CI 0·87, 0·97) and increased levels of circulating vitamin D (RR 0·84; 95 % CI 0·72, 0·97). These results show that whole milk intake might contribute to a higher ovarian cancer risk, whereas low-fat milk, dietary Ca and dietary vitamin D might reduce the risk.

Differences in Auditory Distraction between Adults and Children: A Duplex-mechanism Approach.

Differences in the impact of irrelevant sound on recall performance in children (aged 7-9 years old; N = 89) compared to adults (aged 18-22 years old; N = 89) were examined. Tasks that required serial rehearsal (serial and probed-order recall tasks) were contrasted with one that did not (the missing-item task) in the presence of irrelevant sound that was either steady-state (a repeated speech token), changing-state (two alternating speech tokens) and, for the first time with a child sample, could also contain a deviant token (a male-voice token embedded in a sequence otherwise spoken in a female voice). Participants either completed tasks in which the to-be-remembered list-length was adjusted to individual digit span or was fixed at one item greater than the average span we observed for the age-group. The disruptive effects of irrelevant sound did not vary across the two methods of determining list-length. We found that tasks encouraging serial rehearsal were especially affected by changing-state sequences for both age-groups (i.e., the changing-state effect) and there were no group differences in relation to this effect. In contrast, disruption by a deviant sound-generally assumed to be the result of attentional diversion-was evident among children in all three tasks while adults were less susceptible to this effect. This pattern of results suggests that developmental differences in distraction are due to differences in attentional control rather than serial rehearsal efficiency.