ABSTRACT
Low-grade myofibroblastic sarcoma is a malignant tumor arising from myofibroblasts, which has only recently become clearly defined. It represents a rare entity developing in the soft tissues of the head and neck. About 20 cases have been reported in the oral cavity, especially in the tongue and bone, while gingiva as the primary site has been described only twice to date. Diagnostic methods include histology and immunohistochemistry. The present report concerns a case of a 13-year-old female child who presented with gingival nonulcerated swelling that was interpreted for a long time as a gingival fibroma. A low-grade myofibroblastic sarcoma was diagnosed and the patient underwent a segmental osteotomy of the right posterior region of the maxilla. There was no sign of recurrence or metastatic disease during the 12-month postoperative period. HOW TO CITE THIS ARTICLE: Padmawar NS, Bhadange S, Mustilwar RG, et al. Aberrant Location of Low-grade Myofibroblastic Sarcoma of the Gingiva in Posterior Maxilla. Int J Clin Pediatr Dent 2021;14(6):816-819.
ABSTRACT
BACKGROUND: The chances of extrusion of mineral trioxide aggregate (MTA) are quite high if apical barrier is not present in immature pulpless permanent teeth. Platelet-rich fibrin (PRF) enriched with platelets and growth factors serves to accelerate the wound healing of periapical lesion in immature pulpless permanent teeth and also serves as internal matrix to condense MTA. AIM: The aim of the present study was to comprehensively review the clinical success of MTA+PRF in healing of periapical lesions in immature pulpless permanent teeth. MATERIALS AND METHODS: An electronic search for systematic review was conducted in Pubmed/Medline (www.ncbi.nlm.nih.gov), Cochrane (www.cochrane.org), Scopus (www.scopus.com) databases upto 15th January 2020 related to the healing of periapical lesions in permanent teeth with immature apices when combination of MTA+PRF was used. A sample of 10 relevant studies and case reports were identified in our search out of 65. The sampling method was simple random technique. The studies and case reports with Randomised Controlled Trials(RCTs), Invitro studies, Case reports and animal studies in healing of periapical lesion were included in our comprehensive systematic review. RESULTS: The search showed that the combination of MTA+PRF showed faster and definite periapical lesion healing in immature permanent teeth. The follow-up period was also recorded in all the relevant studies and case reports. CONCLUSION: Acclerated bone filling was seen in healing of periapical leions when MTA+PRF was used.
