ABSTRACT
The endobronchial localization of Hodgkin's disease is a rare entity which is often confused with endobronchial tuberculosis in our setting. We report the case of a 16 years old female who presented with 6 months history of dry cough, hemoptysis, dyspnea, dysphagia and dysphonia. The chest radiography showed a mediastinal and pulmonary opacity. The chest CT scan found enlarged mediastinal lymph nodes. The bronchial biopsy and peripheral lymph node biopsy confirmed Hodgkin's disease with endobronchial localization. The patient received chemotherapy (ABVD protocol) and radiotherapy with a favorable follow up.
Subject(s)
Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bronchial Neoplasms/diagnosis , Hodgkin Disease/diagnosis , Adolescent , Biopsy , Bleomycin/therapeutic use , Bronchial Neoplasms/drug therapy , Bronchial Neoplasms/pathology , Dacarbazine/therapeutic use , Doxorubicin/therapeutic use , Female , Follow-Up Studies , Hodgkin Disease/drug therapy , Hodgkin Disease/pathology , Humans , Lymph Nodes/pathology , Tomography, X-Ray Computed , Vinblastine/therapeutic useABSTRACT
Drug hypersensitivity syndrome or Drug Rash with Eosinophilia and Systemic Symptoms or DRESS syndrome is a severe and potentially life-threatening toxidermia. It should be suspected in patients developing cutaneous reaction following drug intake. We report the case of a 45-year old patient treated for pulmonary tuberculosis (TPM+) who developed DRESS syndrom induced by antibacillaries.
