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Zhongguo Zhong Yao Za Zhi ; 30(8): 634-40, 2005 Apr.
Article in Chinese | MEDLINE | ID: mdl-16011292

ABSTRACT

Crataegus oxyacantha (Aubepine, Hawthorn), was used by european herbalist in the first century A. D. It went out fashion as a medicine until the 19th century for heart disease. The leaves, flowers, and berries of hawthorn contain a variety of bioflavonoid-like complexes that appear to be primarily responsible for the cardiac actions of the plant. Bioflavonoids found in C. oxyacantha include oligomeric procyanidins (OPCc), vitexin, quercetin, and hyperoside. The action of these compounds on the cardiovascular system has led to the development of leaf and flower extracts. As described in French pharmacopea, the hyperoside is the marker for quality control.


Subject(s)
Cardiovascular Agents , Cardiovascular Diseases/drug therapy , Crataegus , Phytotherapy , Plants, Medicinal , Animals , Cardiovascular Agents/pharmacology , Cardiovascular Agents/therapeutic use , Crataegus/chemistry , Flowers/chemistry , France , Heart Failure/drug therapy , Humans , Plant Extracts/isolation & purification , Plant Extracts/pharmacology , Plant Extracts/therapeutic use , Plants, Medicinal/chemistry
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