Variations in long-term outcome reporting among offspring followed up after lifestyle interventions in pregnancy: a systematic review.

Background Mothers and their offspring may benefit from lifestyle interventions during pregnancy. We systematically reviewed the literature to map and evaluate the quality of long-term offspring outcomes in follow-up cohorts of randomised controlled trials (RCTs). Methods We searched MEDLINE, EMBASE, CINAHL, Database of Abstracts of Reviews of Effects and Cochrane Central (until March 2019) for all RCTs evaluating any lifestyle (diet or exercise) intervention during pregnancy and their follow-up cohorts. Two reviews evaluated the extracted outcomes using two standardised assessment tools, one for quality of reporting (score range 0-6) and another for the variation in outcome selection. We extracted data in duplicate and reported using natural frequencies, medians, ranges, means and standard deviation (SD). Results We captured 30 long-term offspring outcomes reported in six articles (four studies). Offspring anthropometric measurements were the most commonly reported outcomes. There was a large variation in the measurement tools used. The mean overall quality score for outcome reporting was 3.33 (SD 1.24), with poor reporting of secondary outcomes and limited justification for the choice of the reported outcomes. Most studies showed selective reporting for both their primary and secondary outcomes. Conclusion The quality of reporting for long-term offspring outcomes following lifestyle interventions in pregnancy is varied with evidence of selective outcome reporting. Developing a core outcome set will help to reduce the variations in outcome reporting to optimise future research.

Does vehicle color influence the risk of being passively involved in a collision?

BACKGROUND: Bright- or light-colored vehicles are sometimes regarded as safer because they are presumably more visible. We examined the effect of vehicle color on the risk of being passively involved in a collision. METHODS: This paired case-control study used data from the Spanish database of traffic crashes. We selected those collisions from 1993 to 1999 in which only one of the drivers committed an infraction. The violators constituted the control group; the other drivers formed the case group. Information about the color of the vehicle and other confounding variables was also collected. RESULTS: When white was compared with the remaining colors, a protective estimate was obtained (adjusted odds ratio [aOR] = 0.97; 95% confidence interval = 0.94-1.00). The results were similar for light colors (white plus yellow) compared with all remaining colors (aOR = 0.96; 0.94-0.99). The protective effect of light colors was specifically observed for open roads and under daylight conditions. It was stronger in conditions other than good weather (aOR = 0.91; 0.86-0.99) than in good weather conditions. CONCLUSIONS: Light colors (white and yellow) were associated with a slightly lower risk of being passively involved in a collision, although only under certain environmental conditions.