Factors involved in the success and failure of endoscopic dacryocystorhinostomy from our experience.

INTRODUCTION: Chronic dacryocystitis is the condition secondary to permanent lacrimonasal duct stenosis (LNDS) that generates epiphora and recurrent conjunctivitis. Endoscopic dacryocystorhinostomy (EDCR) is a more natural route than the external route and offers higher success rates than the laser technique. We value this centre's experience in this procedure. PATIENTS AND METHODS: A retrospective review was carried out in our centre of the medical records of adult patients undergoing EDCR due to LNDS between 1995 and 2019. The minimum follow-up period required after surgery was 6 months. RESULTS: Over 297 months, 167 EDCR procedures were performed on 156 patients, with an average age of 65.7 ±â€¯11.6 years and a male/female ratio of 1/1.98. The functional improvement was 86%, with an anatomical success rate of 87%. Lack of clinical improvement statistically significantly correlated with the age of the patient and the time since onset of the LNDS, the presence of concomitant systemic (especially diabetes mellitus) or ophthalmological disease, the intraoperative finding of a thickened tear sac and absence of drainage of the tear sac when marsupialised. Longer-term stent carriers in the rhinostomy had poorer outcomes. There were no postoperative complications of interest. CONCLUSIONS: EDCR is an effective and safe technique, based on stable anatomical references. Failure rate seems to be multifactorial and should be considered in older, multipathological patients, with a long duration of the condition.

Factores implicados en el éxito y fracaso de la dacriocistorrinostomía endoscópica desde nuestra experiencia / Factors involved in the success and failure of endoscopic dacryocystorhinostomy from our experience

Introducción: La dacriocistitis crónica es la patología secundaria a la estenosis del conducto lacrimonasal (ECLN) permanente, generando epífora y conjuntivitis de repetición. La dacriocistorrinostomía endoscópica (DCRE) supone una vía más natural que la vía externa y ofrece tasas de éxito superiores a la técnica láser. Valoramos la experiencia de este centro en este procedimiento. Pacientes y métodos: Se efectuó una revisión retrospectiva de los registros médicos en pacientes adultos sometidos a DCRE por ECLN entre 1995 y 2019 en nuestro centro. El período de seguimiento mínimo requerido después de la cirugía fue de seis meses. Resultados: En 297 meses se efectuaron 167 procedimientos de DCRE sobre 156 pacientes, con una edad media de 65,7±11,6 años y una relación hombre/mujer de 1/1,98. La mejoría funcional fue del 86%, con una tasa de éxito anatómico del 87%. La ausencia de mejoría clínica se correlacionó de forma estadísticamente significativa con la edad del paciente y el tiempo de evolución de la ECLN, la presencia de patología concomitante sistémica (especialmente diabetes mellitus) u oftalmológica, el hallazgo intraoperatorio de un saco lacrimal engrosado y la ausencia de drenaje del mismo al marsupializarlo. Los pacientes con peor respuesta fueron portadores de stents en la rinostomía durante más tiempo. No existieron complicaciones postoperatorias de interés. Conclusiones: La DCRE es una técnica eficaz y segura, fundamentada en referencias anatómicas estables. La incidencia de fracasos parece multifactorial y debe contemplarse en pacientes añosos, pluripatológicos y con largo tiempo de evolución de la enfermedad. (AU)

Introduction: Chronic dacryocystitis is the condition secondary to permanent lacrimonasal duct stenosis (LNDS) that generates epiphora and recurrent conjunctivitis. Endoscopic dacryocystorhinostomy (EDCR) is a more natural route than the external route and offers higher success rates than the laser technique. We value this centre's experience in this procedure. Patients and methods: A retrospective review was carried out in our centre of the medical records of adult patients undergoing EDCR due to LNDS between 1995 and 2019. The minimum follow-up period required after surgery was 6 months. Results: Over 297 months, 167 EDCR procedures were performed on 156 patients, with an average age of 65.7±11.6 years and a male/female ratio of 1/1.98. The functional improvement was 86%, with an anatomical success rate of 87%. Lack of clinical improvement statistically significantly correlated with the age of the patient and the time since onset of the LNDS, the presence of concomitant systemic (especially diabetes mellitus) or ophthalmological disease, the intraoperative finding of a thickened tear sac and absence of drainage of the tear sac when marsupialised. Longer-term stent carriers in the rhinostomy had poorer outcomes. There were no postoperative complications of interest. Conclusions: EDCR is an effective and safe technique, based on stable anatomical references. Failure rate seems to be multifactorial and should be considered in older, multipathological patients, with a long duration of the condition. (AU)

Factors involved in the success and failure of endoscopic dacryocystorhinostomy from our experience. / Factores implicados en el éxito y fracaso de la dacriocistorrinostomía endoscópica desde nuestra experiencia.

INTRODUCTION: Chronic dacryocystitis is the condition secondary to permanent lacrimonasal duct stenosis (LNDS) that generates epiphora and recurrent conjunctivitis. Endoscopic dacryocystorhinostomy (EDCR) is a more natural route than the external route and offers higher success rates than the laser technique. We value this centre's experience in this procedure. PATIENTS AND METHODS: A retrospective review was carried out in our centre of the medical records of adult patients undergoing EDCR due to LNDS between 1995 and 2019. The minimum follow-up period required after surgery was 6 months. RESULTS: Over 297 months, 167 EDCR procedures were performed on 156 patients, with an average age of 65.7 ± 11.6 years and a male/female ratio of 1/1.98. The functional improvement was 86%, with an anatomical success rate of 87%. Lack of clinical improvement statistically significantly correlated with the age of the patient and the time since onset of the LNDS, the presence of concomitant systemic (especially diabetes mellitus) or ophthalmological disease, the intraoperative finding of a thickened tear sac and absence of drainage of the tear sac when marsupialised. Longer-term stent carriers in the rhinostomy had poorer outcomes. There were no postoperative complications of interest. CONCLUSIONS: EDCR is an effective and safe technique, based on stable anatomical references. Failure rate seems to be multifactorial and should be considered in older, multipathological patients, with a long duration of the condition.

Implicación ORL en infecciones por Leishmania / ENT involvement in Leishmania infections

INTRODUCCIÓN: La leishmaniasis comprende un grupo de enfermedades provocadas por parásitos protozoos del género Leishmania que se transmiten mediante la picadura de la hembra de mosquitos flebotomos infectados desde reservorios animales, generando 3 formas clínicas diferentes: cutánea, mucocutánea y visceral. Presentamos los hallazgos en cabeza y cuello de esta enfermedad observados en nuestra área de salud. PACIENTES Y MÉTODOS: Revisión de los últimos 26 años en nuestro hospital, anotando las características clínicas, diagnósticas y terapéuticas de los casos detectados. RESULTADOS: Fueron identificados 13 casos, 7 con síndrome cutáneo, 4 mucocutáneo y 2 visceral o kala azar. Su edad media fue de 53,7 ± 10,8 años. En un 61% de los casos se verificó inmunodeficiencia. La incidencia de la enfermedad fue de 1,5:100.000 habitantes-año, con una prevalencia del 2%. El 69% de los infectados mostraron afectación del área otorrinolaringológica. En 12 casos el diagnóstico se estableció mediante biopsia de las lesiones. El tiempo desde el inicio clínico al diagnóstico osciló entre 3 y 10 meses. Como tratamiento se emplearon compuestos antimoniales en 11 pacientes y anfotericina B en 3, sola o combinada con el anterior. Una forma cutánea se resolvió con escisión de la lesión. El 92% mostró curación clínica y parasitológica. CONCLUSIONES: La leishmaniasis en España genera frecuentes cuadros de afectación cutánea y mucocutánea, a menudo en la piel de cabeza, cara y cuello o mucosa de vías altas. Su presentación clínica es muy variable, debiéndose sospechar ante la ausencia de respuesta a terapias convencionales y en condiciones de inmunodeficiencia

INTRODUCTION: Leishmaniasis comprises a group of diseases caused by protozoan parasites of the genus Leishmania that are transmitted by the bite of infected phlebotomine mosquitoes from animal reservoirs. Three different clinical forms are generated: cutaneous, mucocutaneous and visceral. We present the findings in the head and neck of this disease observed in our health area. PATIENTS AND METHODS: A review of the last 26 years in our hospital, noting the clinical, diagnostic and therapeutic characteristics of the cases detected. RESULTS: Thirteen cases were identified, 7 cutaneous, 4 mucocutaneous and 2 visceral or kala-azar. The mean age was 53.7 ± 10.8 years. Immunodeficiency was identified in 61% of the cases. The incidence of the disease was 1.5:100,000 inhabitants/year, with a prevalence of 2%. Of those infected, 69% had involvement of the ear-nose-throat area. In 12 cases the diagnosis was established by biopsy of the lesions. The time from clinical debut to diagnosis ranged from 3 to 10 months. Antimony compounds were used as treatment in 11 patients and amphotericin B in 3, alone or combined with the former. One cutaneous form resolved with excision of the lesion. Ninety-two percent healed clinically and parasitologically. CONCLUSIONS: Leishmaniasis in Spain frequently entails cutaneous and mucocutaneous involvement, often of the skin of the head, face and neck or upper-airway mucosa. Its clinical presentation varies greatly, and it should be suspected if there is no response to conventional therapies and in conditions of immunodeficiency

ENT involvement in Leishmania infections. / Implicación ORL en infecciones por Leishmania.

INTRODUCTION: Leishmaniasis comprises a group of diseases caused by protozoan parasites of the genus Leishmania that are transmitted by the bite of infected phlebotomine mosquitoes from animal reservoirs. Three different clinical forms are generated: cutaneous, mucocutaneous and visceral. We present the findings in the head and neck of this disease observed in our health area. PATIENTS AND METHODS: A review of the last 26 years in our hospital, noting the clinical, diagnostic and therapeutic characteristics of the cases detected. RESULTS: Thirteen cases were identified, 7 cutaneous, 4 mucocutaneous and 2 visceral or kala-azar. The mean age was 53.7±10.8 years. Immunodeficiency was identified in 61% of the cases. The incidence of the disease was 1.5:100,000 inhabitants/year, with a prevalence of 2%. Of those infected, 69% had involvement of the ear-nose-throat area. In 12 cases the diagnosis was established by biopsy of the lesions. The time from clinical debut to diagnosis ranged from 3 to 10 months. Antimony compounds were used as treatment in 11 patients and amphotericin B in 3, alone or combined with the former. One cutaneous form resolved with excision of the lesion. Ninety-two percent healed clinically and parasitologically. CONCLUSIONS: Leishmaniasis in Spain frequently entails cutaneous and mucocutaneous involvement, often of the skin of the head, face and neck or upper-airway mucosa. Its clinical presentation varies greatly, and it should be suspected if there is no response to conventional therapies and in conditions of immunodeficiency.

Comentario a «Sialolitectomía transoral combinada con sialoendoscopia versus submaxilectomía abierta para el manejo de litiasis hiliares de la glándula submaxilar» / Comments on «Transoral sialolitectomy combined with sialoendoscopy versus open submaxillectomy for the management of hilar lithiasis of the submandibular gland»

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Deformabilidad eritrocitaria patológica en pacientes con sordera súbita / Pathologic erythrocyte deformability in patients with sudden sensorineural hearing loss

Objetivos: Evaluar si las propiedades viscoelásticas de la sangre influyen en la posibilidad de padecer sordera súbita o en la capacidad de responder a un tratamiento específico. Pacientes y métodos: Fueron estudiados 85 oídos de pacientes con sordera súbita, midiéndose el porcentaje de hipoacusia al inicio y el grado de recuperación a los 6 meses tras un tratamiento con corticoides y piracetam. También se anotó la presencia de acúfeno o síntomas vestibulares y se determinó en sangre periférica la filtrabilidad en sangre total (FST) y el índice de rigidez eritrocitaria (IRE). Resultados: La pérdida media al inicio clínico fue del 30,3±19,7% y a los 6 meses del 25,8±39%. En 41 oídos se observó una recuperación auditiva superior al 75% pasado este tiempo. En este grupo -el 48% del total- la FST se elevó y el IRE descendió (p<0,001 en ambos). Los oídos sin acúfeno ni vértigo recuperaron más audición a los 6 meses y mostraron mejoría significativa en su FST y en el IRE. El grado de hipoacusia al inicio se correlacionó con la FST y el de recuperación con el IRE, pero de forma estadísticamente no significativa. Los antecedentes de hipertensión arterial, cardiopatías e hipercolesterolemia fueron los más comúnmente detectados. Hipertensión e hiperuricemia mostraron mayor capacidad de recuperación. Conclusiones: Los parámetros de viscosidad sanguínea FST e IRE se correlacionan bien con el riesgo de padecer sordera súbita y la capacidad de una adecuada recuperación de la misma con terapias reoactivas(AU)

Objective: To evaluate if viscoelastic properties of blood influence suffering sudden sensorineural hearing loss and the capacity to respond after a specific therapy. Patients and methods: A longitudinal prospective study included 85 ears bearing sudden deafness. In them, the mean hearing loss compared to the healthy ear and the recovery ratio were measured at the onset and 6 months after a treatment with corticoids and piracetam. In addition, tinnitus or vestibular symptoms, whole blood filterability (WBF) and erythrocyte deformability -by means of the erythrocyte rigidity index (ERI)- were determined and noted at the beginning and the end of the study. Results: Mean hearing loss was 30.3±19.7% at the onset, and 25.8±39% at the end. Forty-one ears showed a recovery of more than 75%. In these (48% of the entire study group), an increase in WBF and a decrease in ERI were observed (P<.001). Ears without tinnitus or vestibular crisis recovered more hearing at 6 months and showed a significant improvement in WBF and ERI, not detected among patients with these clinical findings. There were good correlations between mean hearing loss at onset and WBF, and between recovery and ERI at 6 months, but without statistical significance. Patients with arterial hypertension, cardiopathy and hypercholesterolemia were the most frequently detected, while hypertension and hyperuricaemia showed a better hearing recovery ratio. Conclusions: The blood viscosity parameters WBF and ERI offer useful information about the risk of suffering sudden deafness and the capacity to recover hearing with reactive therapies(AU)

Pathologic erythrocyte deformability in patients with sudden sensorineural hearing loss.

OBJECTIVE: To evaluate if viscoelastic properties of blood influence suffering sudden sensorineural hearing loss and the capacity to respond after a specific therapy. PATIENTS AND METHODS: A longitudinal prospective study included 85 ears bearing sudden deafness. In them, the mean hearing loss compared to the healthy ear and the recovery ratio were measured at the onset and 6 months after a treatment with corticoids and piracetam. In addition, tinnitus or vestibular symptoms, whole blood filterability (WBF) and erythrocyte deformability -by means of the erythrocyte rigidity index (ERI)- were determined and noted at the beginning and the end of the study. RESULTS: Mean hearing loss was 30.3±19.7% at the onset, and 25.8±39% at the end. Forty-one ears showed a recovery of more than 75%. In these (48% of the entire study group), an increase in WBF and a decrease in ERI were observed (P<.001). Ears without tinnitus or vestibular crisis recovered more hearing at 6 months and showed a significant improvement in WBF and ERI, not detected among patients with these clinical findings. There were good correlations between mean hearing loss at onset and WBF, and between recovery and ERI at 6 months, but without statistical significance. Patients with arterial hypertension, cardiopathy and hypercholesterolemia were the most frequently detected, while hypertension and hyperuricaemia showed a better hearing recovery ratio. CONCLUSIONS: The blood viscosity parameters WBF and ERI offer useful information about the risk of suffering sudden deafness and the capacity to recover hearing with reactive therapies.