Improving the efficiency of estrus synchronization in cows.

Objective: This study aimed to determine the effects of biologically active substances and electrical stimulation of the uterus in cows on the effectiveness of estrus synchronization. Materials and Methods: Ninety (n = 90) Kazakh white-headed cows were synchronized with two injections of gonadotropin-releasing hormone on days 0 and 9 and prostaglandin F2α on day 7. The cows were divided into six groups and, during the protocol, treated with biologically active substances (Tetramag, Selevetum, antiseptic-stimulator Dorogov 2 fraction, groups 2, 3, and 4). Cows in groups 5 and 6 were treated with the same substances but additionally had electrical stimulation of the uterus, while cows in group 1 were left untreated and served as a control. Results: The results have shown that on Day 0, no differences were observed in E2 concentrations between the groups. However, on the 10th day, a significant disparity was noted in the E2 level among cows in group 6 compared to groups 2, 3, 4, and the control group. Conversely, no significant differences were observed between groups 5 and 6. Likewise, the fertility rate in cows from group 6 was significantly higher compared to groups 2, 3, 4, and the control group, with no significant differences between groups 5 and 6. Conclusion: It can be concluded that the utilization of electrical stimulation of the uterus and the inclusion of certain biological substances during the estrus synchronization protocol demonstrate a positive effect on the reproductive performance of beef cattle in Kazakhstan.

Prevalence, Diagnosis and Improving the Effectiveness of Therapy of Mastitis in Cows of Dairy Farms in East Kazakhstan.

In the present work, the prevalence, etiological factors and effective treatment scheme of mastitis in cows of dairy farms "Balke" and "Madi-R" in Eastern Kazakhstan were investigated. In total, 210 heads were investigated on two farms. The incidence of mastitis in cows on dairy farms is not the same in different years. Average clinical mastitis was detected in 35.4% of cows in 2016, 19.6% in 2017, 28.5% in 2018, and in 2019 in 16.4% of cows. The prevalence rates of subclinical mastitis by year had some differences. So, in 2016­36.5% of cows, then in 2017­21.5%, 2018­19.3% and in 2019­22.6%. In cows with udder inflammation, serum calcium 9.37 ± 0.15 mg/% with a range of 8.0 to 10.8 mg/%, phosphorus 3.58 ± 0.07 mg/% (3.0 to 4.3 mg/%), reserve alkalinity 363.46 ± 6.69 mg/% (320 to 440), carotene 0.49 ± 0.03 mg/% (0.220 to 0.988 mg/%), which are in the lower limit of physiological parameters. The drug "Dorob" was tested during the study of comparative effectiveness of treatment methods. The results of the study showed that this drug has anti-inflammatory, antimicrobial and stimulating healing actions. The treatment of the sick cows with catarrhal mastitis has shown that a total of 8 cows have recovered in the control group and 10 cows in the experimental group with the preparation "Dorob". The period of recovery in the control group was 8.8 ± 0.39, and in the experimental group­6.2 ± 0.28 (p < 0.05). The drug does not contain antibiotics and hormonal preparations. The inclusion of the drug in the scheme of treatment allows for effectively treating inflammatory processes in the udder of cows and restoring their productivity with minimal cost of time and money.