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Sci Rep ; 14(1): 2324, 2024 01 28.
Article in English | MEDLINE | ID: mdl-38282060

ABSTRACT

Medical diagnosis through prediction and analysis is par excellence in integrating modern technologies such as the Internet of Things (IoT). With the aid of such technologies, clinical assessments are eased with protracted computing. Specifically, cancer research through structure prediction and analysis is improved through human and machine interventions sustaining precision improvements. This article, therefore, introduces a Protein Structure Prediction Technique based on Three-Dimensional Sequence. This sequence is modeled using amino acids and their folds observed during the pre-initial cancer stages. The observed sequences and the inflammatory response score of the structure are used to predict the impact of cancer. In this process, ensemble learning is used to identify sequence and folding responses to improve inflammations. This score is correlated with the clinical data for structures and their folds independently for determining the structure changes. Such changes through different sequences are handled using repeated ensemble learning for matching and unmatching response scores. The introduced idea integrated with deep ensemble learning and IoT combination, notably employing stacking method for enhanced cancer prediction precision and interdisciplinary collaboration. The proposed technique improves prediction precision, data correlation, and change detection by 11.83%, 8.48%, and 13.23%, respectively. This technique reduces correlation time and complexity by 10.43% and 12.33%, respectively.


Subject(s)
Antifibrinolytic Agents , Internet of Things , Neoplasms , Humans , Neoplasms/diagnosis , Amino Acids , Correlation of Data , Hydrolases
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