ABSTRACT
To achieve early detection of HIV infection, physicians must be aware of symptoms related to HIV infection. Dermatologists, in particular, can play an important role, because more than 90% of patients infected with HIV will develop at least one type of dermatologic disorder, which may be the first indicator of the existence of infection. A 26-year-old male presented with a one-year history of intractable pruritus associated with multiple excoriations and small ulcers. Initially, his condition clinically resembled adult atopic dermatitis. However, no improvement was observed despite treatment including narrowband ultraviolet B (UVB), antihistamine, and topical and systemic corticosteroid. After a week, the patient developed seizures and was diagnosed with diffuse large B-cell lymphoma of the brain. HIV testing was performed, and the patient was revealed to be HIV-positive. He began highly active antiretroviral therapy (HAART), and the pruritus and skin condition improved dramatically. Herein, we report a case of HIV infection for which the presenting sign was intractable pruritus.
Subject(s)
Adult , Humans , Male , Antiretroviral Therapy, Highly Active , Brain , Dermatitis, Atopic , HIV Infections , HIV , Lymphoma, B-Cell , Pruritus , Seizures , Skin , UlcerABSTRACT
No abstract available.
ABSTRACT
No abstract available.
Subject(s)
Humans , Infant , Exanthema , Leukemia , Leukemia, Myeloid, AcuteABSTRACT
Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Subject(s)
Humans , Dermatitis , Dermatitis, Perioral , Metronidazole , Mouth , Nose , TacrolimusABSTRACT
Childhood granulomatous periorificial dermatitis (CGPD) is a distinctive granulomatous form of perioral dermatitis. It is characterized by papular eruptions located around the mouth, nose, and eyes, and rarely present eczematous patches or plaques. Histopathologic examination shows upper dermal and perifollicular granulomatous infiltrates. Herein, we report two cases of CGPD that were presented with erythematous plaques. One patient was treated with 0.03% topical tacrolimus and the other patient with oral metronidazole. The patients responded well to their respective therapies, showing resolution of the lesions.
Subject(s)
Humans , Dermatitis , Dermatitis, Perioral , Metronidazole , Mouth , Nose , TacrolimusABSTRACT
BACKGROUND: Atopic dermatitis (AD) in school-aged children may affect their daily activities and psychological well-being. It can also have a negative impact on the child's behavior. Little is known about the quality of life (QOL) and psychiatric symptoms in school-aged children and their relationship to disease severity. OBJECTIVE: The purpose of this study was to document the impact of AD on QOL and psychiatric symptoms in school-aged children by disease severity. METHODS: Seventy-eight AD patients aged 7approximately19 years were included in this study. Participants completed the Children's Dermatology Life Quality Index (CDLQI), Kovacs' Children's Depression Inventory (CDI), and the Korean Attention-Deficit Hyperactivity Disorder Rating Scale (K-ARS). Disease severity was evaluated using the SCORAD (SCORing Atopic Dermatitis) index. RESULTS: The SCORAD was 28.95+/-17.92 (mean+/-SD), and the CDLQI was 8.04+/-6.29. The CDLQI was significantly correlated with the SCORAD. Psychiatric symptoms (CDI and K-ARS) did not show a correlation with the SCORAD, but they worsened with increasing CDLQI score. There was no statistically significant difference among the different age groups. CONCLUSION: We demonstrated that AD had an impact on school-aged children's QOL and psychological well-being. Severity of AD correlated with QOL decrements, indicating greater QOL impact with greater disease severity. Psychiatric symptoms were more related to subjective impairment of QOL than objective disease severity.
Subject(s)
Child , Humans , Depression , Dermatitis, Atopic , Dermatology , Quality of LifeABSTRACT
BACKGROUND: Dermoscopy has been suggested as a useful tool for diagnosing various skin diseases. Recently, the possibility of using dermoscopy to predict the response to treatment has emerged. OBJECTIVE: The purpose of this study was to determine whether dermoscopic findings corresponded to clinical acne scar types. This study also aimed to discover which dermoscopic findings predict the response to acne scar treatment. METHODS: The dermoscopic findings of 39 participants undergoing atrophic acne scar treatment with fractional photothermolysis were evaluated. Patients were divided into two groups according to the duration of acne scar persistence. RESULTS: Patients with a relatively short duration of acne scar persistence usually achieved better treatment outcomes. Dermoscopic findings showed no obvious differences according to clinical acne scar type. But high hair follicle density can be considered a predictive factor of treatment effects. CONCLUSION: Our study indicated that acne scar improvements can be predicted by dermoscopically observing hair follicle density.
Subject(s)
Humans , Acne Vulgaris , Cicatrix , Dermoscopy , Hair Follicle , Pilot Projects , Skin DiseasesABSTRACT
Rowell's syndrome is a rare entity consisting of lupus erythematosus with associated erythema multiforme-like lesions and characteristic immunological findings, and it was first described by Rowell et al. in 1963. Because of the clinical similarities between subacute cutaneous lupus erythematosus and Rowell's syndrome, it is difficult to clinically distinguish between the annular-polycyclic type of subacute cutaneous lupus erythematosus and Rowell's syndrome. We report a case of 18-year-old woman with systemic lupus erythematosus who presented erythema multiforme-like eruptions on both thighs. Simultaneously, she developed urticarial-like rashes on her trunk consistent with atypical skin lesion of lupus erythematosus. She also developed a positive antinuclear antibody with speckled pattern and positive anti-Ro antibody.
