Do Silver Zones reduce auto-related elderly pedestrian collisions? Based on a case in Seoul, South Korea.

Inaugurated in 2007, in Seoul, South Korea, the Silver Zone is a designated pedestrian safety zone for the elderly that adopts speed limit measures such as traffic signage and road surface markings. In this study, we empirically investigate the effectiveness of the Silver Zone in two respects: first, whether the establishment of the Silver Zone has lowered the number of elderly pedestrian collisions, and second, whether Silver Zones are established in the appropriate areas, that is, those with the highest frequency of such collisions. From our quasi-experimental statistical analysis, Difference-in-Difference, we learn that the Silver Zone has no effects on reducing elderly pedestrian collisions. From our spatial statistical analyses-Kernel Density mapping and Bivariate Moran's I-we found a spatial mismatch between the frequency of senior pedestrian-vehicular collisions and the location of Silver Zones. For better performance of the Silver Zone system, we suggest additional types of physical measures to be integrated into the Silver Zone system. Municipal-level comprehensive master plan for Silver Zone system is also necessary, under which local governments should use periodic surveys to inventory and prioritise the locations of highest elderly pedestrian-vehicular collisions.

Massive Hemoptysis due to Endotracheal Hemangioma: A Case Report and Literature Review.

Tracheal hemangioma is a rare benign vascular tumor in adults. We reported a case of massive hemoptysis caused by a cavernous hemangioma in a 75-year-old man. This is the first report, to our knowledge, of a tracheal cavernous hemangioma that presented with massive hemoptysis. The lesion was removed with a CO2 laser under rigid laryngoscopy. Endovascular tumors, such as tracheobronchial hemangiomas, should be considered a diagnostic option in cases of massive hemoptysis without a significant underlying lung lesion.

Daio-Orengedokuto inhibits HMG-CoA reductase and pancreatic lipase.

To evaluate the antihyperlipidemic activities of Orengedokuto (OT) and Daio-Orengedokuto (DOT), the inhibitory effects of these polyprescriptions on HMG-CoA reductase and pancreatic lipase and on the rat hyperlipidemic model induced by Triton WR-1339 were measured. OT potently inhibited HMG-CoA reductase but did not inhibit lipase. Among their ingredients, Coptidis Rhizoma was the most potent inhibitor, followed by Rhei Rhizoma. The HMG-CoA reductase-inhibitory activity of 80% EtOH extract was superior to that of water extract. However, DOT potently inhibited HMG CoA-reductase as well as pancreatic lipase. In the rat hyperlipidemic model induced by Triton WR-1339, OT and DOT decreased serum total cholesterol and low-density lipoprotein cholesterol levels. DOT also decreased serum triglyceride levels, but OT did not decrease it. These results suggest that the antihyperlipidemic activity of DOT may originate from the inhibition of pancreatic lipase as well as HMG-CoA reductase.