The oxidative stress-dependent pulmonary inflammation of inhalable multi-walled carbon nanotube-containing nano-concrete dust and its comparison with conventional concrete dust and DQ12.

Nano-concrete, which is an admixture of nanomaterials in concrete recipes, has been investigated to overcome the limitations of existing concrete, such as its stability and strength. However, there is no information on the human health effects of broken-down dust released during the construction and demolition efforts. In this study, we prepared an inhalable fraction of multi-walled carbon nanotube-containing nano-concrete dust and performed comparative toxicity studies with conventional concrete dust and DQ12 using a rat intratracheal instillation model. Although the recipes for concrete and nano-concrete are entirely different, the pulverized dust samples showed similar physicochemical properties, such as 0.46-0.48 µm diameter and chemical composition. Both concrete and nano-concrete dust exhibited similar patterns and magnitudes, representing acute neutrophilic inflammation and chronic active inflammation with lymphocyte infiltration. The toxicity endpoints of the tested particles at both time points showed an excellent correlation with the reactive oxygen species levels released from the alveolar macrophages, highlighting that alveolar macrophages are the primary target cells and that the oxidative stress paradigm is the main toxicity mechanism of the tested particles. In addition, the toxicity potentials of both concrete and nano-concrete dust were more than 10 times lower than that of DQ12.

Selected Strength Properties of Coal Bottom Ash (CBA) Concrete Containing Fly Ash under Different Curing and Drying Conditions.

This study aims to evaluate the effect of curing and drying conditions on the strength properties of concrete containing coal bottom ash (CBA) and fly ash as substitutes for fine aggregates and cement, respectively. The strength properties of the concrete including CBA and fly ash were evaluated under two different curing and drying conditions: saturated surface-dry (SSD) conditions and oven-dried conditions at curing ages of 28 and 91 days. The natural fine aggregates of the mixtures were replaced by CBA fine aggregates at 25%, 50%, 75%, and 100% by volume. In addition, the cement in the mixtures was partly replaced with fly ash at 20% and 40%. The experimental program included the measurement of the unit weight, compressive strength, splitting tensile strength, flexural strength, and ultrasonic pulse velocity of the concrete. The test results showed that the compressive strength, splitting tensile strength, and flexural strength decreased as the CBA content increased under both SSD and oven-dried conditions. The curing and drying conditions of the concrete with CBA and fly ash considerably influenced the reduction in the compressive, splitting, and flexural tensile strengths of the concrete. Additionally, the experimental results showed that fly ash insignificantly contributed to the reduction in the strength properties under both SSD and oven-dried conditions. Finally, the relationships between ultrasonic pulse velocity and the splitting tensile strength, flexural tensile strength, and compressive strength were investigated.