ABSTRACT
In a prospective randomized study the durability of tunnelled and non-tunnelled central venous catheters was investigated in children with malignant diseases. Twenty children were included in the study but four (two in each group) had to be excluded; three because the entry criteria turned out not to be fulfilled and one because of lack of data. The median duration of the tunnelled catheters was 224 days with a range of 25-846 days which was significantly longer than that of conventional catheters (39.5 days, range 9-228 days). In addition six of eight conventional catheters were accidentally removed whereas all catheters in the tunnelled group had to be removed via a small incision. Three cases of catheter related sepsis, two in the tunnelled group and one in the conventional group, were registered. The corresponding number of infections per catheter days were 1 in 1189 days and 1 in 522 days, respectively. In conclusion cuffed, tunnelled central venous catheters are less prone to displacement than traditional percutaneous central venous catheters when used in children with malignant diseases.
Subject(s)
Catheterization, Central Venous , Neoplasms/therapy , Adolescent , Catheterization, Central Venous/adverse effects , Catheters, Indwelling/adverse effects , Child , Child, Preschool , Equipment Failure , Female , Humans , Male , Prospective StudiesABSTRACT
Ethylene glycol poisoning is a rare event in Denmark. The diagnosis can only be made as one of exclusion, since serum ethylene glycol measurements are not made in Danish laboratories. A case report of ethylene glycol poisoning is presented here. Diagnostic problems and treatment are described.