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Braz J Phys Ther ; 22(1): 77-81, 2018.
Article in English | MEDLINE | ID: mdl-28743567

ABSTRACT

BACKGROUND: There is evidence of hypertensive effects caused by anabolic androgenic steroids (AAS). A single exercise session promotes the acute reduction of blood pressure, but the effects of AAS on this phenomenon are unknown. OBJECTIVES: To investigate the post-exercise blood pressure response in androgenic-anabolic steroid users. METHODS: Thirteen AAS users (23.9±4.3 years old) and sixteen controls (22.1±4.5 years old) performed a session of aerobic exercise. Heart rate and blood pressure were assessed before exercise and during a 60min post-exercise resting period. Repeated ANOVA measures were used to determine differences between the groups. RESULTS: While the control group had a significant reduction in post-exercise systolic blood pressure of up to 13.9±11.6mmHg at 40min, this phenomenon was limited among AAS users who reached a maximum of 6.2±11.5mmHg at 60min. The between groups comparison revealed significant higher post-exercise hypotension (PEH) for the control group at 30min (-12.9±14.1mmHg versus -2.9±7.6mmHg), 40min (-13.9±11.6mmHg versus -2.5±8.3mmHg), 50min (-13.9±13.9mmHg versus -5.0±7.9mmHg) and 60min (-12.5±12.8mmHg versus -6.2±11.5mmHg). There was no significant diastolic PEH in any of the groups. CONCLUSIONS: This study demonstrated impaired systolic post-exercise hypotension as a new adverse effect of AAS usage.


Subject(s)
Anabolic Agents/therapeutic use , Androgens/therapeutic use , Post-Exercise Hypotension/prevention & control , Post-Exercise Hypotension/physiopathology , Testosterone Congeners/therapeutic use , Adult , Anabolic Agents/pharmacology , Androgens/pharmacology , Blood Pressure/drug effects , Case-Control Studies , Heart Rate/drug effects , Heart Rate/physiology , Humans , Systole/drug effects , Systole/physiology , Testosterone Congeners/pharmacology , Young Adult
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