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1.
Am J Dermatopathol ; 38(3): 231-5, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26894776

ABSTRACT

Cervical chondrocutaneous remnants are congenital, benign, and rare neck masses. We present here for the first time the immunohistochemical profile of Pacinian corpuscles present in cervical chondrocutaneous remnants, removed, and localized in the territory of the second branchial arch from a 5-year-old girl. We have performed immunohistochemistry to analyze these sensory corpuscles using a battery of antibodies including markers for each corpuscle constituent. The central axon was immunoreactive for neurofilaments, neuron-specific enolase, and neural cell adhesion molecule; the Schwann-related cells forming the inner core displayed immunoreactivity for S100 protein, vimentin, and neural cell adhesion molecule; the outer core and the capsule were positive for vimentin, epithelial membrane antigen, and glucose transporter 1. These results are discussed in topographical differences. Moreover, a brief update about the structure, protein composition, and development of Pacinian corpuscles was performed.


Subject(s)
Branchial Region/abnormalities , Pacinian Corpuscles/abnormalities , Biomarkers/analysis , Child, Preschool , Female , Humans , Immunohistochemistry
2.
J Oral Maxillofac Surg ; 62(2): 155-63, 2004 Feb.
Article in English | MEDLINE | ID: mdl-14762747

ABSTRACT

PURPOSE: The objective of this study was to analyze the principal variables that determine the choice of the method of treatment and the outcome in condylar fractures. MATERIALS AND METHODS: We conducted a retrospective analysis of 104 mandibular condyle fractures to analyze and determine the relation between the principal clinical variables and the postoperative results. All patients underwent a clinic-radiologic investigation focusing on fracture remodeling, evolution, dental occlusion, and symmetry of the mandible. We analyzed the influence of the preoperative clinical variables (level of fracture, treatment, postoperative physical therapy, displacement and dislocation, comminution, loss of ramus height, patient age, gender, etiology, occlusion, status of dentition, and presence of facial and mandibular fractures) over the postoperative results and outcome. RESULTS: The principal factors that determined the treatment decision were the level of the fracture and the degree of displacement. The level of the fracture influenced the degree of preoperative coronal and sagittal displacement (neck fractures had greater medial and anterior displacement than head and subcondylar fractures) and the treatment applied. The functional improvement obtained by open methods was greater than that obtained by closed treatment. Open treatment increased the incidence of postoperative condylar deformities and mandibular asymmetry. CONCLUSION: The variables that influenced the method of treatment and predicted the prognosis are the level of fracture, degree and direction of displacement of the fractured segments, age, medical status of the patient, concomitant injuries, and status of dentition.


Subject(s)
Fracture Fixation/methods , Mandibular Condyle/injuries , Mandibular Fractures/therapy , Temporomandibular Joint/injuries , Adolescent , Adult , Aged , Aged, 80 and over , Child , Child, Preschool , Decision Making , Female , Humans , Joint Dislocations/classification , Joint Dislocations/therapy , Male , Mandibular Condyle/surgery , Mandibular Fractures/classification , Middle Aged , Outcome and Process Assessment, Health Care , Retrospective Studies , Temporomandibular Joint/surgery , Treatment Outcome
3.
Ann Otol Rhinol Laryngol ; 112(7): 647-50, 2003 Jul.
Article in English | MEDLINE | ID: mdl-12903687

ABSTRACT

Blue rubber bleb nevus is a rare entity consisting of distinctive angiomas in the skin and gastrointestinal tract, leading to occult or profound gastrointestinal bleeding and chronic anemia. The efficacy has been documented of systemic treatment with corticoids, interferon, vincristine, and, more recently, subcutaneous octreotide in the presence of active lesion proliferation or disseminated intravascular coagulation. A case of blue rubber bleb nevus syndrome with oral hemangiomas in a 24-year-old woman is reported. The surgical specimens were subjected to immunohistochemical study, which showed all of the hemangiomas to be in an inactive phase.


Subject(s)
Nevus, Blue/pathology , Tongue Neoplasms/pathology , Adult , Factor VIII/analysis , Female , Hemangioma, Cavernous/pathology , Humans , Immunohistochemistry , Ki-67 Antigen/analysis , Mouth Neoplasms/pathology , Neoplasms, Multiple Primary/pathology , Nevus, Blue/chemistry , Platelet Endothelial Cell Adhesion Molecule-1/analysis , Tongue Neoplasms/chemistry
4.
Med Oral ; 8(1): 61-5, 2003.
Article in English | MEDLINE | ID: mdl-12556726

ABSTRACT

The chemical burns in the oral mucosa as consequence of accident of suicide attempt are relatively frequent. The evolution of the repairing process is conditioned by the quality and concentration of the caustic as by the location and time exposure of the affected region. At this report, we document a form of conservative treatment for the limitation of mouth opening, which the patient presented after swallowing a detergent acid. In order to obtain a minimal oral opening, a screwed cone, whose action mechanism was acting as a cradle between both jaws, was used. Once achieved a 10 mm opening, it was possible to use an external distractor to accomplish a continuous traction.


Subject(s)
Burns, Chemical/etiology , Caustics/adverse effects , Cicatrix/chemically induced , Contracture/chemically induced , Mouth Diseases/chemically induced , Mouth/injuries , Adult , Burns, Chemical/therapy , Cicatrix/therapy , Contracture/therapy , Female , Humans , Mouth Diseases/therapy
5.
Ann Otol Rhinol Laryngol ; 111(8): 751-3, 2002 Aug.
Article in English | MEDLINE | ID: mdl-12184600

ABSTRACT

The presence of multiple giant cell lesions in the maxillofacial region is suggestive of hyperparathyroidism or neurofibromatosis. A case of synchronous, multiple peripheral giant cell granulomas is reported, bilaterally affecting the mandibular gums and also the upper right maxillary gingival mucosa, without concomitant systemic disease. Only 2 cases of central giant cell granulomas, and no cases of peripheral giant cell granulomas exhibiting similar characteristics, have been reported in the literature to date.


Subject(s)
Gingival Diseases/diagnosis , Granuloma, Giant Cell/diagnosis , Jaw Diseases/diagnosis , Gingival Diseases/epidemiology , Granuloma, Giant Cell/epidemiology , Humans , Jaw Diseases/epidemiology , Male , Middle Aged
6.
Plast Reconstr Surg ; 109(3): 877-85; discussion 886-7, 2002 Mar.
Article in English | MEDLINE | ID: mdl-11884800

ABSTRACT

The purpose of this article is to present the authors' experience with the use of porous polyethylene ultrathin sheets for orbital floor reconstruction. Thirty-two patients with orbital floor fractures were treated with porous polyethylene ultrathin sheets. Sixteen cases corresponded to orbitozygomatic fractures, 11 cases corresponded to pure orbital floor fractures, and five corresponded to panfacial fractures. The subciliary approach was used in 15 patients and the transconjunctival approach in nine; another three patients were operated on through a preexisting eyebrow wound, two were operated on with a subtarsal approach, two were operated on through an eyebrow extension of a facial wound, and one patient was operated on through the facial wound. Intraoperatively, all patients received a prophylactic dose of intravenous antibiotics. Postoperatively, 24 patients received amoxicillin clavulanate for 5 to 7 days, two patients received clindamycin, and six patients received no antibiotics. Enophthalmos was corrected in 15 of 24 patients (62.5 percent), and hypoglobus in nine of 11 (82 percent). Diplopia was resolved in 25 of 28 patients (89.3 percent) with preoperative impairment. Extrinsic eye movement impairment was resolved in 25 of 27 patients (92.6 percent). A preoperative visual acuity deficit was present in four patients (12.5 percent) and was resolved in one (from 20/100 to 20/20). Visual acuity improved in one patient (from 20/60 to 20/30). In the other two patients, visual acuity remained altered (from 20/30 to 20/30). One patient (3.1 percent) suffered blindness induced by surgery. Nine of 26 patients (34.6 percent) had residual infraorbital nerve hypesthesia and five (19.2 percent) had residual paresthesias. Postoperatively, epiphora was present in six patients (18.8 percent) and ectropion in five (15.6 percent). Although there was no statistical significance between the surgical approach and the presence of epiphora (p = 0.211) and ectropion (p = 0.422), patients who were treated using the transconjunctival approach suffered reduced ectropion (0 percent) compared with patients treated using the subciliary approach (20 percent). However, patients treated using the transconjunctival approach suffered increased epiphora (22.2 percent) compared with those treated with the subciliary approach (13.3 percent). There were four cases (12.5 percent) of postoperative facial infections. Two of these cases were resolved with systemic antibiotics, one was resolved with bone sequestrum resection, and one patient needed removal of the implant. Orbital infections were related in all cases to titanium osteosynthesis miniplates or skull bone graft. When comparing patients who were treated with and without antibiotics, no statistical differences (p = 0.958) were found relative to the presence of infections. Correction of hypoglobus is technically easier than enophthalmos, because enophthalmic correction requires a wide, deep subperiosteal dissection and implant positioning, posterior to the equator of the globe, with the inherent risk of orbital apex injury.


Subject(s)
Biocompatible Materials , Orbital Fractures/surgery , Orbital Implants , Plastic Surgery Procedures/methods , Polyethylenes , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Prosthesis Design
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