Increased serum reverse triiodothyronine in patients with hyperemesis gravidarum.

Thyroid function and pituitary responsiveness to TRH were studied in patients with hyperemesis gravidarum. Serum T3 and T4 concentrations were normal. Serum TBG levels in hyperemesis were normal for gestation, and the T4:TBG ratio was in the euthyroid range. In all patients a normal TSH response to TRH was found. Mean serum rT3 concentration was increased by 31% as compared to a control group of normal pregnant women (P less than 0.001). The data suggest that in patients with hyperemesis gravidarum there is: (a) normal function of the thyroid gland and pituitary-thyroid axis, (b) an enhanced peripheral conversion of T4 to rT3.

[Secondary sterility after artificial abortion].

PIP: 336 women suffering from secondary sterility were subjected to examination and observation. The cause of sterility was inflammatory etiology in 78.9% of the cases, 43.5% of which were provoked by induced abortion. A high incidence of complications with regard to impaired fertility has been noted among abortions of 1st pregnancies. After the interruption of the 1st pregnancy, twice as many sterile women were found in the group with late menarache (44) as in the group with the normal appearance of the 1st menstruation (21). As abortion is considered to be a major cause of fertility complications, the reduction of the number of abortions is considered important in the prophylaxis of these problems.^ieng