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MMW Munch Med Wochenschr ; 119(44): 1441-4, 1977 Nov 04.
Article in German | MEDLINE | ID: mdl-412088

ABSTRACT

The efficacy of a new low dosage trimethoprim-sulfamoxole combination (Supristol) was tested in a joint therapeutic study in 6 medical clinics or departments and in a general practice. A good therapeutic result (healing) was achieved in about 80% of the 143 patients included in the trial. The preparation was well tolerated. Symptoms of intolerance appeared in only 2% of the cases. It is assumed that the low dosage of the preparation influences the tolerance favorably without affecting the efficacy.


Subject(s)
Sulfonamides/therapeutic use , Trimethoprim/therapeutic use , Acute Disease , Adolescent , Adult , Aged , Bacterial Infections/drug therapy , Blood Sedimentation , Child , Chronic Disease , Clinical Trials as Topic , Drug Combinations , Drug Synergism , Female , Gastrointestinal Diseases/drug therapy , Humans , Leukocyte Count , Male , Middle Aged , Respiratory Tract Infections/drug therapy , Sulfonamides/administration & dosage , Sulfonamides/adverse effects , Trimethoprim/administration & dosage , Trimethoprim/adverse effects , Urinary Tract Infections/drug therapy
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