[Human Y chromosome: structure and biological role]. / Zmogaus Y chromosoma: struktura ir biologinis vaidmuo.

Y chromosome differs from other human chromosomes. It is found in cells of the male persons only. Different human phenotypes are associated with non-recombinant region of Y chromosome. This chromosome is of great significance in the human sex determination and the development of male gametes (spermatogenesis). Testes develop in embryos which have the Y chromosome, and ovaries develop in embryos which have no Y chromosome. SRY (sex-determining region of the Y chromosome) gene determines the male phenotype. Translocation of this gene determines sex reversal. The aim of this article was to review the structure and biological functions of the human Y chromosome.