1.
J Antibiot (Tokyo)
; 60(3): 216-9, 2007 Mar.
Article
in English
| MEDLINE
| ID: mdl-17446696
ABSTRACT
Seven new related compounds named bispolides A1, A2, A3, B1, B2a, B2b and B3, have been found in a culture of Microbispora sp. A34030, isolated from a Malaysian soil sample. The planar structures were elucidated to be new 20-membered ring macrodiolide antibiotics on the basis of MS and NMR spectroscopic analyses. These antibiotics showed a good anti-MRSA activity in vitro.