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1.
Schmerz ; 33(4): 337-346, 2019 Aug.
Article in German | MEDLINE | ID: mdl-31098706

ABSTRACT

BACKGROUND: In industrialized countries, chronic back pain is referred to as the "number one common disease". OBJECTIVES: Are there any indications of different outcomes of chronic back pain patients when treated with a multimodal, interdisciplinary pain therapy (MMSTh) compared to physiotherapy-physical therapy? MATERIALS AND METHODS: Entrance and final examination by means of survey, questionnaires and physical tests in the intervention and control group, evaluation and comparison of the results. RESULTS: The intervention group showed very significant improvements in all tests. In contrast, the control group achieved only partial improvements in physical parameters and quality of life. This resulted in clear group differences in favor of the MMSTh. In terms of patient satisfaction, the control group showed a better result than the intervention group. CONCLUSIONS: Treatment with MMSTh is superior to standard physiotherapy-physical. Due to the extensive, proven positive effect on many pain-causing and pain-preserving factors, multimodal pain centers should be used more frequently in chronic back pain patients.


Subject(s)
Back Pain , Chronic Pain , Physical Therapy Modalities , Back Pain/drug therapy , Back Pain/therapy , Chronic Pain/drug therapy , Chronic Pain/therapy , Combined Modality Therapy , Humans , Quality of Life , Surveys and Questionnaires , Treatment Outcome
2.
Eur J Clin Microbiol Infect Dis ; 35(7): 1165-9, 2016 Jul.
Article in English | MEDLINE | ID: mdl-27126331

ABSTRACT

The purpose of this investigation was to analyze the burden of respiratory syncytial virus (RSV)-related hospitalizations in infants and children with congenital heart disease (CHD) over three consecutive RSV seasons. Retrospectively, all children with hemodynamically significant (HS-CHD) and not significant (HNS-CHD) CHD born between 2004 and 2008 at a tertiary care university hospital and identified by ICD-10 diagnoses were included. Data on RSV-related hospitalizations over the first three years of life covering at least three RSV seasons (November-April) were analyzed. The overall incidence of RSV-related hospitalization was 9.6 % (58/602), without a statistically significant difference between HS-CHD and HNS-CHD (7.3 % vs. 10.4 %; p = 0.258). Recommendation of palivizumab prophylaxis did not influence the RSV hospitalization rates between groups. Patients with HS-CHD and early surgery were significantly less often hospitalized due to RSV compared to those with delayed surgery (1.3 % vs. 14.3 %; p = 0.003). The median duration of hospitalization was 8.5 days (HS-CHD: 14 vs. HNS-CHD: 7 days; p = 0.003). Thirteen patients (22.4 %) were admitted to the intensive care unit (ICU), for a median of 10 days. The median age at admission was 2 months, with a significant difference between HS-CHD and HNS-CHD (6 vs. 2 months; p = 0.001). The majority (97 %) of RSV-related hospitalizations occurred before 12 months of age. Patients with HS-CHD had a significantly more severe course of RSV disease and were older at the time of hospitalization. Early surgery seemed to significantly reduce the risk of RSV hospitalization during the first RSV season.


Subject(s)
Heart Defects, Congenital/complications , Heart Defects, Congenital/epidemiology , Respiratory Syncytial Virus Infections/complications , Respiratory Syncytial Virus Infections/epidemiology , Respiratory Syncytial Virus, Human , Seasons , Child, Preschool , Cost of Illness , Female , Follow-Up Studies , Heart Defects, Congenital/therapy , Hospitalization , Humans , Infant , Intensive Care Units , Male , Respiratory Syncytial Virus Infections/therapy , Retrospective Studies , Risk Factors
3.
Schmerz ; 29(6): 625-31, 2015 Dec.
Article in German | MEDLINE | ID: mdl-26337691

ABSTRACT

BACKGROUND: In a survey of all adult inpatients at the Wilhelminen Hospital in Vienna and the Klagenfurt Clinic on Lake Wörthersee, data on pain prevalence, the most frequent sites of pain, pain intensity, pain type, effect of pain on patients, pain evaluation on the various wards, pain precipitating factors, and patient satisfaction were collected. MATERIALS AND METHODS: All inpatients > 18 years were questioned using a questionnaire developed by the investigators at the Department for Anesthesia, Intensive Care, and Pain Medicine at the Wilhelminen Hospital. RESULTS: A pain prevalence of 45.7% was found at the Wilhelminen Hospital and of 40.8% at the Klagenfurt Clinic. Women reported pain significantly more often than men. No significant difference was found between surgical and conservative treatment wards in terms of pain prevalence. Patients on conservative treatment wards reported significantly higher current pain intensity than those in surgical departments. The most common areas of pain were joints and bones. A score >3 in the ID pain questionnaire was reached by 8.8% (Wilhelminen Hospital) and 4.0% (Klagenfurt Clinic) of participants. Pain influenced mood, mobility, and nighttime sleep, and was intensified by the daily clinical routine. CONCLUSION: Overall, it was demonstrated that the majority of patients at both hospitals were satisfied with the pain management. However, pain management in conservative treatment disciplines must not be neglected. More intense current pain, a worse quality of life, and a trend toward lower patient satisfaction indicate that analgesic treatment in nonsurgical disciplines should be optimized.


Subject(s)
Hospitalization/statistics & numerical data , Pain Management/statistics & numerical data , Pain/epidemiology , Adult , Aged , Aged, 80 and over , Austria , Cross-Sectional Studies , Female , Health Care Surveys , Humans , Male , Middle Aged , Pain/classification , Pain/psychology , Pain Management/psychology , Pain Measurement/classification , Pain Measurement/statistics & numerical data , Patient Satisfaction , Quality of Life/psychology , Risk Factors , Surveys and Questionnaires
4.
Schmerz ; 29(4): 440-4, 2015 Aug.
Article in German | MEDLINE | ID: mdl-26024644

ABSTRACT

BACKGROUND: Until recently the measurement of pain in cognitively impaired patients represented a neglected field in the diagnostics and treatment of pain. Investigations indicate a prevalence of pain in nursing home residents of between 45 % and 80 %. MATERIAL AND METHODS: This study investigated the reliability of the German translation of the Doloshort scale and compared it with the visual analog scale (VS). The aim of this study was to determine the practical applicability of this scale in the clinical routine and to calculate the intrarater reliability (retest) and interrater reliability. RESULTS: The interrater and intrarater reliability of the Doloshort scale was between 0.949 and 0.970. There was a highly significant correlation between the values of the Doloshort scale and the VAS. CONCLUSION: The Doloshort scale is a well suited measurement instrument for the evaluation of pain in cognitively impaired patients. Because of the short form only simple instructions are necessary and it has a high acceptance with users.


Subject(s)
Chronic Pain/classification , Chronic Pain/diagnosis , Cognitive Dysfunction/complications , Cognitive Dysfunction/psychology , Dementia/complications , Dementia/psychology , Pain Measurement/methods , Pain Measurement/statistics & numerical data , Psychometrics/statistics & numerical data , Translating , Aged , Aged, 80 and over , Chronic Pain/psychology , Documentation , Female , Germany , Homes for the Aged , Humans , Male , Mental Status Schedule/statistics & numerical data , Nursing Homes , Observer Variation , Reproducibility of Results
6.
Acta Paediatr ; 90(6): 664-70, 2001 Jun.
Article in English | MEDLINE | ID: mdl-11440101

ABSTRACT

UNLABELLED: In neonates, despite poor platelet function in various in vitro tests, closure times (CTs) in PFA-100 measurements are shorter than in adults. Neonates have a higher polymeric von Willebrand factor (vWF). They also have a higher haematocrit and higher white blood cell count than adults. which may interfere with the evaluation of platelet and vWF function by means of the PFA-100 in neonates. To assess the role of different blood constituents on neonatal CTs, red blood cell, platelet and white blood cell counts in cord blood were modified. These modifications did not provide any evidence that the difference in number between adult and neonatal blood cells was responsible for shorter neonatal CTs. In further experiments, platelets and/or vWF were inhibited by means of abciximab and anti-vWF antibody, and mixing experiments with neonatal platelet-rich and platelet-poor plasma were performed. The results showed that short cord blood PFA-100 CTs were caused by a constituent of neonatal platelet-poor plasma, probably the neonatal high multimeric vWF. CONCLUSION: This study demonstrates that CTs in neonates are dependent on the same components, platelets and vWF, as in adults, making it likely that the PFA-100 can be used in neonates in the same way as in adults to investigate platelet and vWF function.


Subject(s)
Blood Platelets/physiology , Erythrocytes/physiology , Infant, Newborn/blood , Leukocytes/physiology , Platelet Function Tests , von Willebrand Factor/physiology , Abciximab , Adult , Antibodies/pharmacology , Antibodies, Monoclonal/pharmacology , Fetal Blood , Humans , Immunoglobulin Fab Fragments/pharmacology , Platelet Aggregation Inhibitors/pharmacology , von Willebrand Factor/immunology
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