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1.
Rev Epidemiol Sante Publique ; 63(6): 387-93, 2015 Dec.
Article in French | MEDLINE | ID: mdl-26547669

ABSTRACT

BACKGROUND: The study aimed to determine the clinical forms of tuberculosis and therapeutic outcome of anti-tuberculosis treatment in the context of HIV-tuberculosis co-infection. METHODS: A retrospective cohort of 120 HIV-positive patients with tuberculosis and 297 HIV-negative patients with tuberculosis attending the Kabinda Center was followed from 2010 to June, 30th 2013. The logistic regression model identified the determinants of a defavorable outcome after initiation of tuberculostatics. RESULTS: The proportion of female patients was higher in the co-infected group compared with the non-co-infected group (60.8% versus 42.7%, P<0.001). HIV-seropositive patients had more forms of pulmonary smear-negative (39.2% versus 25.3%, P<0.002) and extra-pulmonary (38% versus 35%, P<0.002) tuberculosis than HIV-negative patients. HIV-positive serology (OR: 3.13, 95%CI: 1.72-5.69) and age of patients more than 41 years (OR: 3.15, 95%CI: 1.36-7.29) were associated with an unfavorable outcome. CONCLUSION: This study highlights the usefulness of a systematically determining immunological status in co-infected patients and a timely and systematic ARV treatment, together with early diagnosis of tuberculosis. It also emphasizes the importance of adherence to support measures in order to improve tuberculosis treatment outcomes in co-infected patients.


Subject(s)
Antitubercular Agents/therapeutic use , Coinfection/drug therapy , HIV Infections/drug therapy , Tuberculosis/drug therapy , Adult , Coinfection/epidemiology , Democratic Republic of the Congo/epidemiology , Female , HIV Infections/complications , HIV Infections/epidemiology , HIV-1 , Humans , Male , Retrospective Studies , Treatment Outcome , Tuberculosis/complications , Tuberculosis/epidemiology , Young Adult
2.
Mali Med ; 30(2): 25-32, 2015.
Article in French | MEDLINE | ID: mdl-29927142

ABSTRACT

OBJECTIVE: To identify predictors of cesarean delivery in the Kinkanda general hospital. METHOD: Cross-sectional study conducted from 1st January 2012 to 31st December 2012, on women in labor who delivered at the maternity of Kinkanda. Predictors of cesarean delivery were identified by using binary logistic regression. RESULTS: A uterine height of at least 33 cm at induction of labor (AOR 3.93 95% CI 2.04 to 7.59; p <0.001), primiparity (AOR 2.1 95%CI:1.06 to 4.15; p = 0.033), non-membership of the pregnant woman to this particular health center area (AOR 4.26 95%CI 2.16 to 8.42; p <0.001) and a weight of the newborn of at least 4000g (AOR 7.8 95%CI 2.3 to 26.44; p <0.001) were identified as risk factors for cesarean delivery. CONCLUSION: Primiparity, uterine height of at least 33 cm, living in another health area than the Matadi area and fetal macrosomia are the main predictors of cesarean delivery during the year 2012 at the Kinkanda general hospital.


OBJECTIF: Identifier les prédicteurs de l'accouchement par césarienne à l'Hôpital Général de Kinkanda. MÉTHODE: Etude transversale analytique réalisée du 01 janvier au 31 décembre 2012, auprès de parturientes ayant accouché à la maternité de l'Hôpital Général de Kinkanda. Les variables prédictives de l'accouchement par césarienne ont été mises en évidence à l'aide d'une régression logistique binaire. RÉSULTATS: Une hauteur utérine d'au moins 33 cm au déclenchement du travail (ORA : 3,93 IC95% : 2,04 ­ 7,59 ; p < 0,001), la primiparité (ORA :2,1 IC95% :1,06 ­ 4,15 ; p= 0,033), la non appartenance de la parturiente à la zone de santé (ORA : 4,26 IC95% : 2,16 ­ 8,42 ; p < 0,001) et le poids du nouveau- né avec au moins 4000g (ORA : 7,8 IC95% : 2,3 ­ 26,44 ; p< 0,001) ont été identifiés comme des facteurs prédictifs de l'accouchement par césarienne. CONCLUSION: La primiparité, la hauteur utérine d'au moins 33 cm, l'appartenance à une autre zone de santé que celle de l'Hôpital Général de Kinkanda et la macrosomie fœtale sont les principaux prédicteurs de la césarienne au cours de l'année 2012 à l'Hôpital Général de Référence de Kinkanda.

3.
Rev Epidemiol Sante Publique ; 62(3): 201-6, 2014 Jun.
Article in French | MEDLINE | ID: mdl-24880569

ABSTRACT

BACKGROUND: The study aimed to identify factors associated with the survival of patients receiving antiretroviral therapy. METHODS: A historic cohort of HIV patients from two major hospitals in Goma (Democratic Republic of Congo) was followed from 2004 to 2012. The Kaplan-Meier method was used to describe the probability of survival as a function of time since inclusion into the cohort. The log-rank test was used to compare survival curves based on determinants. The Cox regression model identified the determinants of survival since treatment induction. RESULTS: The median follow-up time was 3.56 years (IQR=2.22-5.39). The mortality rate was 40 deaths per 1000 person-years. Male gender (RR: 2.56; 95 %CI 1.66-4.83), advanced clinical stage (RR: 2.12; 95 %CI 1.15-3.90), low CD4 count (CD4 < 50) (RR: 2.05; 95 %CI : 1.22-3.45), anemia (RR: 3.95; 95 %CI 2.60-6.01), chemoprophylaxis with cotrimoxazole (RR: 4.29, 95 % CI 2.69-6.86) and period of treatment initiation (2010-2011) (RR: 3.34; 95 %CI 1.24-8.98) were statistically associated with short survival. CONCLUSION: Initiation of treatment at an early stage of the disease with use of less toxic molecules and an increased surveillance especially of male patients are recommended to reduce mortality.


Subject(s)
Antiretroviral Therapy, Highly Active , HIV Infections/drug therapy , HIV Infections/mortality , Adult , Antiretroviral Therapy, Highly Active/statistics & numerical data , Cohort Studies , Democratic Republic of the Congo/epidemiology , Epidemiologic Factors , Female , HIV-1 , Humans , Lost to Follow-Up , Male , Middle Aged , Survival Rate
4.
Ann. afr. méd. (En ligne) ; 5(3): 1068-1074, 2012. tab
Article in French | AIM (Africa) | ID: biblio-1259165

ABSTRACT

Contexte. Le paludisme est un probleme majeur de sante publique en Republique Democratique du Congo. L'utilisation de la moustiquaire impregnee d'insecticide (MII) compte parmi les options les plus efficaces retenues pour lutter contre ce fleau. Cette pratique est encore faible dans la communaute et loin d'approcher le seuil de 60fixe par le sommet d'Abuja. Objectif. Identifier les determinants de l'utilisation de la MII par les enfants de moins de cinq ans a Kinshasa Materiel et methodes. Etude de type transversale; conduite entre le 05 et le 20 aout 2008; dans la zone de sante de Lemba a Kinshasa; sur un echantillon de 299 menages. L'unite statistique retenue dans l'etude etait le menage disposant d'au moins un enfant de moins de cinq ans. La prevalence de l'utilisation de la MII a ete estimee; et la regression logistique a permis d'en identifier les determinants. Resultats. La frequence d'utilisation de la MII dans la population d'etude etait de 42;5(IC95: 36;9 - 48;1). Les determinants de son utilisation identifies etaient : la taille du menage (p= 0;032); l'utilisation d'alternatives a la MII (OR : 0;27 ; IC95:0;15 - 0;48 ; p 0;001) ; l'exposition aux p


Subject(s)
Child , Democratic Republic of the Congo , Insecticide-Treated Bednets , Malaria
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