[Takayasu's arteritis and retroperitoneal fibrosis: a case report]. / Maladie de Takayasu et fibrose rétropéritonéale : une nouvelle observation.

The authors report a 38-year-old young Moroccan woman with retroperitoneal fibrosis (RPF) associated with Takayasu's disease. The RPF was diagnosed in the presence of an acute renal failure requiring placement of double J catheters while an abdominal CT scan was suggestive of RPF. The diagnosis of Takayasu's disease was suspected three years later when the patient presented with right upper extremity dysesthesia. Aortic angiography showed evidence of typical inflammatory arteritis involvement with bilateral regular and concentric stenosis of axillary arteries and a left, smoothly narrowed primitive carotid artery, and left renal artery partial occlusion. The patient was treated with prednisone (0.5mg/kg per day) with a marked improvement. The association between RPF and Takayasu's disease is very rare, and only five cases have been reported in the literature. These two diseases share similarities in some of the etiologic factors and anatomic localizations.

[Systemic lupus erythematous revealed by an acute psychotic episode]. / Un trouble psychotique aigu révélant un lupus érythémateux systémique.

INTRODUCTION: Psychotic disorders are classical in systemic lupus and are listed among American College of Rheumatology (ARA) criteria. They are rarely inaugural and can compromise diagnosis, especially if they are isolated. CLINICAL CASE: A 20-old-year woman was hospitalized for an acute psychotic disorder of two weeks duration with a degradation of the general status. Physical examination revealed intense osteo-tendon reflexes with a right Babinski sign. Brain MRI visualized a nodular low signal T1, T2 and high signal T2 flair in the left centrum semi-ovale. Blood counts showed lymphopenia. Antinuclear antibody and anti-DNA native antibody were positive. The clinical course favorable after treatment using oral corticosteroids, an neuroleptic and an antidepressant. CONCLUSION: Systemic lupus is a potential diagnosis for any atypical psychiatric symptoms in young women.

[Eales disease and tuberculous allergy]. / Maladie de Eales et allergie tuberculinique.

The authors report the case of a 25-year-old woman who presented unilateral Eales disease associated with biologically confirmed pulmonary tuberculosis. The patient, from a family with a history of tuberculosis, showed a painless and abrupt decrease in visual acuity of the right eye with venous and arterial vasculitis. Fluorescein angiography confirmed the existence of peripheral ischemia and vascular abnormalities. The biological exam showed a positive PPD and the BK was isolated. Antibiotic and corticosteroid drugs were used in the treatment. The clinical, immunopathological and therapeutic aspects of this disease are discussed.

[Bilateral anterior uveitis and acute tubulointerstitial nephritis (TINU syndrome). A case report]. / Uvéite antérieure bilatérale et néphrite tubulo-interstitielle aiguë (TINU syndrome). A propos d'un cas.

We describe a case of TINU Syndrome. A 17 year-old girl presented four weeks after an acute tubulo-interstitial nephritis with renal failure a bilateral anterior uveitis. Renal function improved spontaneously. Investigation failed to reveal systemic or infectious diseases. The treatment with oral and topical corticosteroids was successful for the uveitis.

Immunogenicity of oral poliovirus vaccine administered in mass campaigns versus routine immunization programmes.

Reported are the results of a study to investigate the immunogenicity of oral poliovirus vaccine (OPV) when administered in mass campaigns compared with that following routine immunization programmes. For this purpose, paired sera were collected from a cohort of children before and after a mass vaccination with OPV in Morocco in 1987. Serum samples and information on vaccination status and other confounding factors that could influence antibody responses to OPV were collected. Neutralizing antibody titres to poliovirus types 1, 2 and 3 were determined using a standardized assay. OPV doses administered exclusively during the mass campaign were consistently associated with higher type-specific seroprevalence rates than the same number of doses administered in the routine programme. These findings could not be attributed to differences in confounding factors. Enhanced secondary spread of vaccine virus may have occurred but could not be demonstrated because of limitations in the study design. Mass campaigns appear to be highly effective in raising the dose-related poliovirus type-specific immunity of the population above that achieved by the routine immunization programme. Our findings support the continued use of mass campaigns as an adjunct to routine programmes in order to both enhance and catalyse current efforts to achieve the global eradication of poliomyelitis by the year 2000.

PIP: Reported are the results of a study to investigate the immunogenicity of oral poliovirus vaccine (OPV) when administered in mass campaigns compared with that following routine immunization programs. For this purpose, paired sera were collected from a cohort of children before and after a mass vaccination with OPV in Morocco in 1987. Serum samples and information on vaccination status and other confounding factors that could influence antibody responses to OPV were collected. Neutralizing antibody titers to poliovirus types 1, 2, and 3 were determined using a standardized assay. OPV doses administered exclusively during the mass campaign were consistently associated with higher type-specific seroprevalence rates than the same number of doses administered in the routine program. These findings could not be attributed to differences in confounding factors. Enhanced secondary spread of vaccine virus may have occurred but could not be demonstrated because of limitations in the study design. Mass campaigns appear to be highly effective in raising the dose-related poliovirus type-specific immunity of the population above that achieved by the routine immunization program. These findings support the continued use of mass campaigns as an adjunct to routine programs in order to both enhance and catalyze current efforts to achieve the global eradication of poliomyelitis by the year 2000. (author's)

[Retinal detachment in children]. / Décollement de rétine de l'enfant.

During the period January 1985-June 1990, 333 cases of retinal detachment were operated. Thirty cases (9%) were children aged between 5 to 15 years. Retinal detachment was due to developmental abnormalities: myopia, retinoschisis, inherited cataract and glaucoma in 71.4%. Ocular trauma was found in 28.5%. Peripheral vitreoretinal degenerations were found in 82.8%. Reattachment of the retina was achieved in 77.1% of cases. Best visual acuity was 0.4 or better in 40.7% of eyes.