ABSTRACT
The article analyses the results of surgical treatment of 227 patients with osteomyelitis of the foot bones. The peculiarities of the course of the disease, determined by the anatomical and functional features and the concomitant pathological conditions, are evaluated. Comparative appraisal of various methods of examination showed the radionuclide method to be most informative. The peculiarities of surgical operations in pyoinflammatory diseases of the foot bones, which are due to the necessary preservation of a segment of the foot for subsequent correction, call for obligatory application of combined necrectomy and a complex of agents with polyfunctional activity in addition to the traditional mechanical methods of treatment of the bone defect. The results of complex treatment were good in 72%, satisfactory in 23%, and poor in 5% of patients.
Subject(s)
Foot Diseases/diagnostic imaging , Foot Diseases/surgery , Osteomyelitis/diagnostic imaging , Osteomyelitis/surgery , Adult , Chronic Disease , Combined Modality Therapy , Drug Combinations , Erythromycin , Female , Foot Diseases/drug therapy , Gentamicins/therapeutic use , Humans , Male , Middle Aged , Orthopedics/methods , Osteomyelitis/drug therapy , Peptide Hydrolases/therapeutic use , Radionuclide Imaging , Serine Endopeptidases , Treatment OutcomeABSTRACT
Sipralynate is a powder containing the broad spectrum antibiotic sisomicin, the enzyme protease C and the polymer carrier sodium alginate with a drainage capacity promoting wound regeneration. The clinical trials with sipralynate showed that it was highly efficient in the treatment of patients with suppurative infections of the soft tissues and ossa pedis osteomyelitis. The tolerance was good.
