ABSTRACT
The paper describes the clinical, morphological, and immunohistochemical characteristics of 13 granular cell tumors of the upper airway. These tumors are shown to have virtually the same histological and immunohistochemical features as granular cell tumors at another site. The histogenesis of these tumors is discussed. There are currently a number of more or less solid grounds for considering them as neurogenic tumors to be close to schwannomas. At the same time one cannot ignore the fact that there is morphological and immunohistochemical evidence for that the granular cell tumors have rather cytotypical than histotypical properties, which cannot implicitly assign them to nerve tissue tumors. Most likely, the granular cell tumors belong to a histogenetically heterogeneous mixed group, in this connection their place in the classification of tumors needs further investigation, by applying the criteria developed by Russian histologists and oncomorphologists.
Subject(s)
Granular Cell Tumor/pathology , Mixed Tumor, Malignant/pathology , Respiratory Tract Neoplasms/pathology , Adolescent , Adult , Child , Granular Cell Tumor/classification , Humans , Male , Middle Aged , Mixed Tumor, Malignant/classification , Neurilemmoma/classification , Neurilemmoma/pathology , Respiratory Tract Neoplasms/classificationABSTRACT
The state of pulmonary circulation in patients with chronic bronchitis depends on the presence of obstruction, its progression, development of pulmonary hypertension, cor pulmonale and its decompensation. The authors recommend to administer nitrates of prolonged action to such patients.
Subject(s)
Bronchitis/diagnosis , Hypertension, Pulmonary/diagnosis , Adolescent , Adult , Aged , Bronchitis/complications , Bronchitis/drug therapy , Bronchitis/physiopathology , Chronic Disease , Hemodynamics/drug effects , Humans , Hypertension/diagnosis , Hypertension/drug therapy , Hypertension/etiology , Hypertension/physiopathology , Hypertension, Pulmonary/drug therapy , Hypertension, Pulmonary/etiology , Hypertension, Pulmonary/physiopathology , Male , Middle Aged , Nitroglycerin/therapeutic use , Pulmonary Circulation/drug effects , Pulmonary Emphysema/diagnosis , Pulmonary Emphysema/drug therapy , Pulmonary Emphysema/etiology , Pulmonary Emphysema/physiopathology , Pulmonary Heart Disease/diagnosis , Pulmonary Heart Disease/drug therapy , Pulmonary Heart Disease/etiology , Pulmonary Heart Disease/physiopathologySubject(s)
Pulmonary Fibrosis/diagnosis , Adolescent , Female , Humans , Pulmonary Fibrosis/drug therapyABSTRACT
Combined findings in 89 patient over 20 with an interatrial septum defect (IASD) have shown that the frequency of pulmonary hypertension increases with age. Electrocardiographic criteria of pulmonary hypertension do not allow a reliable diagnosis with pressures below 50 mm Hg. Tone I amplitude, Q - Tone I duration, the extent of splitting and correlation of Tone II components cannot be used as PCG criteria of pulmonary hypertension either. The Q - "systolic murmur peak" interval decreases as pulmonary arterial pressure goes up. Systolic murmur amplitude is not relevant for the diagnosis of either the IASD, or pulmonary hypertension. Diastolic murmurs associated with secondary IASD are a more frequent finding, but show no distinctive features.
Subject(s)
Heart Septal Defects, Atrial/complications , Hypertension, Pulmonary/complications , Adult , Atrial Fibrillation/complications , Bundle-Branch Block/complications , Electrocardiography , Heart Septal Defects, Atrial/diagnosis , Hemodynamics , Humans , Middle Aged , PhonocardiographySubject(s)
Lung/diagnostic imaging , Pneumonectomy , Adult , Aged , Chronic Disease , Female , Follow-Up Studies , Humans , Lung Diseases/diagnostic imaging , Lung Diseases/surgery , Male , Middle Aged , RadiographyABSTRACT
The analysis of data obtained in the investigation of functions of the pulmonary blood flow in 44 patients prior to and following segmentary and combined resections of the lungs fulfilled for bronchiectasis has shown that almost all the patients with bronchiectasis have the disturbed hemodynamics of the small circulation circuit. The direct relation was shown between the duration of the disease, spread of the pathological process and the degree of lung hypertension. It has been found that a resection within the limits of 6 lung segments fails to exert a negative influence on hemodynamics of the small blood circulation circuit and allows prevention of progressing pulmonary hypertension in most of the patients.
Subject(s)
Bronchiectasis/physiopathology , Pneumonectomy , Pulmonary Circulation , Adult , Bronchiectasis/surgery , Female , Follow-Up Studies , Hemodynamics , Humans , Hypertension, Pulmonary/physiopathology , Hypertension, Pulmonary/surgery , MaleSubject(s)
Bronchitis/physiopathology , Hemodynamics , Adolescent , Adult , Chronic Disease , Humans , Middle Aged , Pulmonary CirculationABSTRACT
The investigation performed has revealed moderate pulmonary hypertension associated with adaptation of the organism to changed conditions of blood circulation in the lungs. Greatly elevated pressure in the lung artery in response to physical exercise allowed to make a conclusion of practically complete mobilization of compensatory reserves of the right portion of the heart. The changes in the functional state of the remaining lung are evaluated as compensatory ones aimed at the maintenance of a sufficient square surface for gas exchange.
