[Defects in cellular immunity in patients with dermatophytosis]. / Defekt v celulárnej zlozke imunity u pacientov s epidermofýciou.

The authors examined in a group of 24 patients with epidermophytosis, refractory to general and local antimycotic treatment, persisting for 2-4 years, the immunity profile and compared the results with those in a group of healthy subjects. Epidermophytosis was diagnosed on the basis of the clinical picture, microscopic and cultivation examinations. The authors revealed in the patients with epidermophytosis a defect in the cellular immunity component, while there was no defect in the humoral component. They revealed also a shift in the proteins of the inflammatory phase which confirmed the long-term inflammatory process of the disease. In the conclusion the authors recommend to examine in patients with prolonged epidermophytosis refractory to general and local antimycotic treatment the immunological profile, and if there is a defect of cellular immunity despite antimycotic treatment to administer also immunostimulating preparations.