ABSTRACT
Conventional port planning techniques for radiation therapy do not adequately determine the superior and inferior limits of prostatic tumor. A localization device has been devised which provides better boost volume localization. The accuracy of this device has been confirmed by computed axial tomography.
Subject(s)
Prostatic Neoplasms/radiotherapy , Radiotherapy/instrumentation , Humans , Male , Prostate/diagnostic imaging , Prostatic Neoplasms/diagnostic imaging , RadiographySubject(s)
Dysgerminoma/therapy , Testicular Neoplasms/therapy , Adult , Castration , Drug Therapy/methods , Dysgerminoma/diagnostic imaging , Dysgerminoma/pathology , Humans , Male , Neoplasm Staging , Prognosis , Radiotherapy/methods , Testicular Neoplasms/diagnostic imaging , Testicular Neoplasms/pathology , Tomography, X-Ray Computed , UltrasonographyABSTRACT
Radiation therapy for early laryngeal cancer offers an excellent probability of cure as well as preservation of vocal function. Reported failure rates range from 9 to 21% in patients with T1 lesions, and from 28 to 44% in those with T2 lesions, the majority of whom are subsequently salvaged by surgery. Results obtained at the Radiotherapy Center of the University of Wisconsin Hospitals in 44 patients during the period from 1960 to 1972 yielded failure rates of 21% in patients with T1 tumors and 38% in patients with T2 tumors at 5 years. Five of the eight recurrences were salvaged with surgery yielding an overall tumor control rate of 93%. The larynx was preserved in 82% of the cases. Determinate 5-year survival was 91% in T1 cases and 86% in T2 cases. Failure rates at 3 years were 18% for T1 tumors and 30% for T2 lesions. These results are in conflict with those reported by Brandenburg and Rutter as being 46% and 60% respectively. Ultimate success in the treatment of laryngeal cancer rests in the full cooperation between surgeons and radiotherapists.
Subject(s)
Carcinoma, Squamous Cell/radiotherapy , Laryngeal Neoplasms/radiotherapy , Neoplasm Recurrence, Local/epidemiology , Vocal Cords , Carcinoma, Squamous Cell/mortality , Evaluation Studies as Topic , Follow-Up Studies , Humans , Laryngeal Neoplasms/mortality , Neoplasm Metastasis , Neoplasm Staging , Time Factors , Vocal Cords/radiation effectsSubject(s)
Cell Survival/radiation effects , Cell Count , Cell Line , Dose-Response Relationship, Radiation , Hypoxia , Oxygen , Time FactorsABSTRACT
Bipedal lymphography was used as part of the initial staging evaluation of 145 patients with Hodgkin's disease. Histologic correlation was available in 131 patients. The accuracy of interpretation was 95%. A review of other large series confirms that at least 85%-90% accuracy can be expected. Reasons for false positive and false negative interpretations are discussed.
Subject(s)
Hodgkin Disease/diagnostic imaging , Lymphography , Biopsy , Hodgkin Disease/diagnosis , Humans , Lymphography/methodsABSTRACT
Bipedal lymphangiography was performed in 116 selected patients with primary endometrial malignancy since 1970. A total of 32 were interpreted as positive and 84 as negative. Although histologic confirmation of nodal interpretation was seldom obtained, short term follow-up indicates that a positive interpretation is associated with an extremely poor prognosis. Lymphangiograms are recommended in all stage I patients except those with well differentiated histology, a small corpus, and no deep myometrial invasion. This study is also recommended for all stage II and III patients and for selected patients with stage IV disease.
Subject(s)
Lymphography , Uterine Neoplasms/diagnostic imaging , Adenocarcinoma/diagnostic imaging , Adenocarcinoma/pathology , Female , Humans , Lymphatic Metastasis , Uterine Neoplasms/pathologySubject(s)
Carcinoma, Squamous Cell/radiotherapy , Laryngeal Neoplasms/radiotherapy , Adult , Aged , Female , Humans , Male , Middle Aged , Radiotherapy, High-Energy , Time FactorsABSTRACT
Pretreatment staging laparotomy in carcinoma of the uterine cervix has been advocated because surgical staging may detect disease not apparent clinically. An analysis of survival and local control data from previously reported large series of patients with carcinoma of the uterine cervix shows that surgical staging does not increase survival rates. It is likely that surgical staging may also increase morbidity from therapy.
