[Multiple endocrine neoplasia type IIa]. / Prikaz bolesnice multiplom endokrinom neoplazijom tipa dva-A

A gradual manifestation first of parathyroid and then od thyroid and adrenal endocrinopathy in 38-year old female patient, with the syndrome of Multiple Endocrine Neoplasia (MEN) type IIa--Sippl syndrome, is presented. The first diagnosis was hyperparathyroidism, which is unusual in this syndrome, as only a half of the patients affected with MEN IIa have hyperparathyroidism. The diagnosis of medullary thyroid carcinoma is operatively established. The syndrome is diagnosed after the manifestation of the clinical signs of pheochromocytoma. This syndrome is hereditary in autosomal and dominant way. Our patient is the first member in the risk family: the family medical history of our patient was negative. As this syndrome can appear in the age range from 2-67, we intend to make the screening of all the members of the patient's family.

[The significance of radioisotope methods in the diagnosis of liver hemangiomas]. / Znacaj radioizotopskih metoda u dijagnostici hemangioma jetre.

A growing use of ultrasonography for the examination of abdominal organs has resulted in an easier detection of hemangioma-like focal benign changes in the liver. Such cases ask for further diagnosis. Apart from other methods, the diagnosis of hemangiomas is possible by in vivo technetium-labeled erythrocytes. The authors present the erythrocyte labeling technique and the scintigraphic method carried out in 44 patients. On the basis of the obtained results they conclude that scintigraphy can be successfully used for the diagnosis of hemangiomas, especially if the changes seen by ultrasonography are big enough for the scintigraphy. If they are below 20 mm only tomography (SPECT) with labeled erythrocytes is to be considered.