[Origin of rectosigmoid cancer from precancerous processes]. / Vurkhu proizkhoda na rektosigmoidniia rak ot predrakovite protsesi

Three hundred sixty two patients with rectosigmoid cancer are examined by rectoromanoscopy and biopsy in order to establish those of them with manifestations of a proceeding precancer process. Cancer, originated on the base of single polypus was established in 50,94 per cent and 7,54 per cent in relation with preceeding generalized polyposis, in 30,19 per cent malignant villose tumor is concerned, in 4,71 per cent -- cancer, originated on the base of preceeding ulcerohemorrhagic proctocolitis and in only 1,91 per cent -- malignant chronic fibrosclerosed hemorrohoids. Precancer process is established in 29,29 per cent in all of the examined 362 patients with rectosigmoid cancer and in 70,71 per cent of the cases no manifestations of preceeding precancer disease was established, i.e. the malignancy ratio with established precancerosis towards malignancy without established precancerosis is approximately 1 : 2,5. That fact requires acute attention in all cases with established precancerosis of the terminal segment of large intestine, treatment without delay and dispensary control.

[Clinical trial of the preparation Caved S in treating peptic ulcer]. / Klinichno izpitvane na preparata Caved S pri lechenie na iazvenata bolest

The observations upon the therapeutic effect of Caved S preparation are reported, being a combination of deglycyrrhizinated liquorice, alkalizing substances and vagolytic drugs. The clinical trial of the medicine reveals it to be with a quick effect on the subjective complaints good tolerance and no manifested disturbances on water and electrolyte balance. It is suitable for the treatment of patients with gastric and duodenal ulcers. Ulcer niche roentgenologically is healed in 37,5% of the patients with gastric ulcer and in 33% in the patients with duodenal ulcer. Endoscopically, the niche is healed in 25% of the patients with gastric ulcer and in 28,5%--with duodenal ulcer. The medicine is with no effect in cases of gastric callous ulcer, as well as with pyloric stenosis.