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Zoolog Sci ; 25(8): 806-10, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18795814

ABSTRACT

The mouse mylohyoid muscle belongs to the mastication-related suprahyoid muscle group. It shows a plate-like morphology and forms the mouth floor. There have been no reports on the characteristics of the mouse mylohyoid muscle fibers, and especially on their functional role during ingestion action, and many points remain unclear. We examined the mouse mylohyoid muscle at both the transcriptional and protein levels by RT-PCR, immunohistochemistry, and Western Blotting. MyHC-2b, which is expressed in almost all head and neck muscles and is thought to play a role in rapid mastication movement, was not detected in the mouse mylohyoid muscle. This result suggests that the mouse mylohyoid muscle has a special function and does not directly function during ingestion.


Subject(s)
Mastication/physiology , Masticatory Muscles/physiology , Muscle Contraction/physiology , Muscle Fibers, Skeletal/physiology , Myosin Heavy Chains/metabolism , Protein Isoforms/metabolism , Animals , Blotting, Western , Immunohistochemistry , Mastication/genetics , Mice , Mice, Inbred ICR , Muscle Contraction/genetics , Myosin Heavy Chains/genetics , Protein Isoforms/genetics , RNA, Messenger/genetics , Reverse Transcriptase Polymerase Chain Reaction
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