Kinetics of intravenous L-lactic acid in anaesthetized minipigs under normoxic/normocapnic/normohydrogenaemic conditions.

A mild and transitory increase in L-lactic acid (LAC) levels can be achieved by LAC infusion under normoxic/normocapnic/normohydrogenaemic conditions. This increase is probably sufficient to confer some protection to cholinesterases from inhibition by organophosphates.