[Results of treatment on 56 sarcomas of the uterus between 1953 and 1977 (author's transl)]. / Behandlungsergebnisse von 56 Uterussarkomen der Jahre 1953 bis 1977.

At the Frauenklinik Finkenau Hamburg a total of 56 women were treated for sarcoma of the uterus between 1953 and 1977. Accounting for 1.2% of all malignancies, sarcoma is a rare tumor. The different histological types are analysed with respect to age distribution, endocrine status, preceding pregnancies, etc. Treatment results over a 15 years period and a subsequent 10 years period were compared. Symptoms and local findings show great variability. Preoperative diagnostic procedures frequently did not result in final diagnosis. The mode of therapy changed over the long period of 25 years. Forty-nine patients were followed up over a period of more than 10 years. In Patients with sarcomas which had derived from preexisting myomas, the 10 year survival rate was 89% (16/18). The total 10 year survival rate was 57% (28/49). Effectiveness of different therapeutic approaches such as operation, irradiation, and cytostatic therapy is demonstrated. Local recurrences and distant metastases usually occurred within 2 years after primary treatment. One case with successful chemotherapy of pulmonary metastases of leiomyosarcoma is demonstrated showing complete remission over a period of 28 months.

[Therapeutic results in cervix carcinomas during the period 1962-1966]. / Behandlungsergebnisse von Kollumkarzinomen im Zeitraum 1962 bis 1966

At the Frauenklinik Finkenau in Hamburg, from 1962 to 1966 a total of 586 women were hospitalised for initial treatment of a carcinoma of the uterine cervix. The results of treatment are compared with those continously published by our clinic since 1946. The absolute 5-year-cure-rate amounted to 59,6%. Stage I was treated by operation, mostly Wertheim, and afterwards, like stages II to IV, with radiation. Cytostatic agents, mostly Trenimon, were applied in addition to initial therapy to about 25% of the patients. Trenimon was also used for recidive-therapy. The value of this additional therapy has been published in another study. The observed complications are described in details. Patients with hydronephorsis have recently been reexamined by X-rays. The absolute 5-year-cure-rate amounted to 88.4% for stage I, to 65,3% for stage II, to 37,4% for stage III and was 0% for stage IV. The relative 5-year-cure-rate of stage I-patients, treated by Wertheim-operation amounted to 95,2%.