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Org Lett ; 15(14): 3666-9, 2013 Jul 19.
Article in English | MEDLINE | ID: mdl-23808546

ABSTRACT

The first enantioselective total syntheses of pygmaeocins B and C have been accomplished using an efficient and highly diastereoselective intramolecular Heck cyclization for the construction of a quaternary stereogenic center and the functionalized A-ring of the natural products as the key step.


Subject(s)
Biological Products/chemistry , Diterpenes/chemistry , Diterpenes/chemical synthesis , Cyclization , Magnetic Resonance Spectroscopy , Stereoisomerism
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