ABSTRACT
OBJECTIVE: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). METHODS: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). RESULTS: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09-1.88). CONCLUSIONS: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation.
ABSTRACT
BACKGROUND: To provide local data on visual acuity and surgical outcomes for cataract surgery performed in an Australian teaching hospital. DESIGN: Continuous audit over 7 years in a public teaching hospital. PARTICIPANTS: A total of 3740 eyes had cataract surgery performed at The Queen Elizabeth Hospital, South Australia, from May 2006 to September 2013. METHODS: Visual acuity and complication rates were recorded for cataract surgery cases operated on between May 2006 and September 2013 on a digital database with data entry contemporaneous with final follow-up. MAIN OUTCOME MEASURES: Visual acuity and surgical complications. RESULTS: Of the patients, 91.4% achieved postoperative best-measured vision better than preoperative best-measured vision. The rate of posterior capsular tear was 2.59%, endophthalmitis was 0.11% and the overall complication rate was 11.7%. CONCLUSIONS: This audit is the first to document modern cataract surgery, overwhelmingly dominated by phacoemulsification in an Australian population and can be used to benchmark cataract surgery outcome in an urban Australian population.
Subject(s)
Hospitals, Teaching/statistics & numerical data , Hospitals, Urban/statistics & numerical data , Intraoperative Complications , Medical Audit , Phacoemulsification/standards , Postoperative Complications , Visual Acuity/physiology , Anesthesia/methods , Anesthetics/administration & dosage , Humans , Phacoemulsification/statistics & numerical data , Prognosis , Quality Assurance, Health Care/standards , Refraction, Ocular/physiology , South Australia/epidemiologyABSTRACT
OBJECTIVE: The aim of this review was to evaluate the evidence for an association between Aspirin use and early age-related macular degeneration (ARMD). METHODS: A literature search was performed in 5 databases with no restrictions on language or date of publication. Four studies involving 10292 individuals examining the association between aspirin and ARMD met the inclusion criteria. Meta-analysis was carried out by Cochrane Collaboration Review Manager 5.2 software (Cochrane Collaboration, Copenhagen, Denmark). RESULTS: The pooled odd ratios showed that Aspirin use was associated with early ARMD (pooled odds ratio 1.43, 95% CI 1.09-1.88). CONCLUSIONS: There is a small but statistically significant association between Aspirin use and early ARMD, which may warrant further investigation.
