[The ultrastructure of the capillaries and pericapillary area in the formations of the rat forebrain in hypokinesia]. / Ul'trastruktura kapilliarov i perikapilliarnoi oblasti v nekotorykh obrazovaniiakh perednego mozga krysy pri gipokinezii.

Capillaries and pericapillary tissue were studied in central and lateral nuclei of amygdala, cingulate cortex, hippocampal fields CA1 and CA3 and sensomotor, cortex in rats, exposed to hypokinesia 40, 90 and 120 days lasted. Changes, growing more numerous and variable in proportion with the time of hypokinesia were found. The most essential changes were hypertrophy of glial elements with either decreased or increased functional activity. Alteration of the endotheliocyte structure, pinocytosis, hypertrophy and increase of nuclear and cytoplasmic osmophilia, decrease of the folding were noted. Capillaries with significantly increased folding and narrow or containing unidentified substance lumen were encountered in 120-days hypokinesia. In limbic structures pericapillary glia is represented mostly with astrocytes, in neocortex-also with oligodendrocytes.

[The ultrastructure of the myelinated fibers of the rat endbrain in hypokinesia]. / Ul'trastruktura mielinovykh volokon konechnogo mozga krysy pri gipokinezii.

Myelin fibres structure in phylogenetically different regions of telencephalon--in hippocampus, cingular cortex and sensomotor cortex of cerebrum of rats, in hypokinesia lasting for 40 and 90 days was studied electron-microscopically. Changes in ultrastructure of myelin fibres in these formations were found which exposed unequally in different regions and depended on the experiment duration. In 40 days hypokinezia changes were noted only in hippocampus and cingular cortex, while in neocortex they were prominent only in 90-days hypokinisia. Moreover, in neocortex changes were different in large and fine fibres, being more prominent in the former.

[Structural organization of the fronto-parietal area of the sensory-motor cortex of the rat brain]. / Strukturnaia organizatsiia frontoparietal'noi zony sensomotornoi kory bol'shogo mozga krysy.

Organizational peculiarities of the frontal-parietal area of the sensomotor cortex are: parvicellularity, alveolar-like distribution of neurons, radial striation of the lower zone, distinctly manifested stratification of the higher zone in the cortical plate, the middle zones contain short axonal pyramidal, stellate and granular neurons. Formation of somato-somatic contacts is specific for interneuronal interaction. Peculiarity of the normal ultrastructure of the neuronal cytoplasm is presence of 2-4 subsuperficial cisterns in the section. In neuropil, which is presented mainly as axo-spinal assymetrical contacts of the I type after Grey, transversal profiles of tightly arranged and collected in fasciculi finest axonal collaterals and terminal dendritic ramifications are revealed.

[Comparative electron microscopic study of the visual cortex neurons of the cat in postnatal ontogeny]. / Sravnitel'noe élektronno-mikroskopicheskooe issledovanie neironov zritel'noi kory mozga koshki v postnatal'nom ontogeneze.

The maturation of layers II-VI of neurons and perineuronal neuropil of the cat visual cortex (field 17) was studied from postnatal day 1 to day 21. The differentiation of large, small (associate) pyramid and stellate neurons was described. During the first postnatal week, the somata of layers II-VI of neurons undergo significant changes, the perikaryal cytoplasm increases in volume. Cell bodies of large pyramidal neurons mature by day 15. During the second postnatal week and almost till day 15, the rough endoplasmic reticulum of small pyramidal and stellate neurons undergoes proliferation; dendritic processes are branching. In stellate neurons the amount of cytoplasmic organelles increases dramatically only after the second postnatal week, and this is presumably induced by the opening of eyes on day 12. The second postnatal week is the period of greatest growth of dendritic, axonal and glial processes in perineural neuropil of layers V-VI. In the perineuronal neuropil of large pyramidal neurons (layers V-VI) there appear symmetric synapses with pyramidal cells, dendritic processes and dendritic spines. This occurs just at the time when kittens first open the eyes. From this time and during postnatal days 15-21, asymmetric synapses appear in the perineuronal neuropil of large pyramidal neurons. In the perineuronal neuropil of small pyramidal and stellate neurons. (layers II-IV), synapses reveal the mature appearance by day 15. After the opening of the eyes and up to postnatal day 21, dendritic growth and spine production occur in the perineuronal neuropil of small pyramidal and stellate neurons.

[Obtaining columns of central nervous system tissue for culture purposes]. / Poluchenie kolonok tkani tsentral'noi nervnoi sistemy dlia tselei kul'tivirovaniia.

A method is described for obtaining nerve tissue columns for further cultivation. Under tissue culture conditions, this method has an advantage of preserving, at early steps of cultivation, the cytoarchitectonic of cerebral cortex which makes an easy identification of nerve cells and a determination of their layer-by-layer localization.