1.
Thromb Res
; 122(1): 27-32, 2008.
Article
in English
| MEDLINE
| ID: mdl-17999935
Subject(s)
Myeloproliferative Disorders/genetics , Polymorphism, Single Nucleotide , Thrombosis/epidemiology , Thrombosis/genetics , Toll-Like Receptor 4/genetics , Adult , Aged , Aged, 80 and over , Bone Marrow Cells/pathology , DNA/genetics , DNA/isolation & purification , Female , Genotype , Humans , Male , Middle Aged , Myeloproliferative Disorders/complications , Risk Factors
2.
Eur J Intern Med
; 18(4): 333-5, 2007 Jul.
Article
in English
| MEDLINE
| ID: mdl-17574112
ABSTRACT
The present study describes a case of severe pulmonary arterial hypertension (PAH) associated with unilateral lung destruction due to bronchiectasis in a patient with common variable immunodeficiency (CVID). Initially, the patient's treatment included antibiotics, oral anticoagulants, diuretics, and immunoglobulin replacement therapy. However, the patient's condition improved significantly only after inhaled iloprost was administered. Three months later, his PAH was almost reversed. The hemodynamic response of our patient suggests that inhaled iloprost may have a role in the treatment of sustained PAH related to unilateral lung destruction.