ABSTRACT
A method of phalloscintigraphy, based on the gamma camera and computerized data processing, is offered. The results of examination of patients are described.
Subject(s)
Impotence, Vasculogenic/diagnosis , Penis/blood supply , Penis/diagnostic imaging , Radionuclide Imaging/methods , Computing Methodologies , Gamma Cameras , Humans , Impotence, Vasculogenic/diagnostic imaging , Male , Penis/drug effects , Penis/physiopathology , Piperazines/therapeutic use , Purines , Sildenafil Citrate , Sulfones , Technetium/administration & dosage , Technetium/blood , Vasodilator Agents/therapeutic useABSTRACT
The activity of the department for emission introscopy of the Research Institute for Medical Instrument-Making ("ZAO VNIIMP-VITA") is described in the article. A list of developed and commissioned devices and instruments for the field of nuclear medicine is presented. Methods of elaboration of some sophisticated instruments and units designed for radio-biochemical and radio-immunologic examinations as well as methods of elaboration of scintillation gamma cameras, tomograph GKS-301T, medical dosimeters and of other devices are also described.
Subject(s)
Nuclear Medicine/instrumentation , Academies and Institutes , Equipment Design , Humans , Image Processing, Computer-Assisted/instrumentation , Radiobiology/instrumentation , Radioimmunodetection/instrumentation , Russia , Scintillation Counting/instrumentation , Tomography, Emission-Computed/instrumentationABSTRACT
The paper provides the optimum algorithms for diagnosing the severity of prestroke cerebral circulatory disorders and determining the poststroke brain lesion extent. It is suggested that various techniques, such as radionuclide diagnosis, Doppler ultrasonography, postural disorder correction should be employed.
Subject(s)
Cerebrovascular Disorders/diagnosis , Algorithms , Cerebrovascular Circulation , Cerebrovascular Disorders/prevention & control , Cerebrovascular Disorders/rehabilitation , HumansABSTRACT
The main clinical and diagnostic tasks while studying cerebrovascular diseases have been defined and set on the basis of analysis of the biophysical and pathophysiological factors and parameters that characterize the cerebral circulation in health and disease. The currently available physioengineering methods and means for evaluating cebral hemodynamics. Proposals to design new equipment and to improve the existing one and recommendations how to use them while examining the cerebral circulation in various clinical situations are given.
Subject(s)
Cerebrovascular Circulation , Biophysical Phenomena , Biophysics , Cerebrovascular Disorders/diagnosis , Cerebrovascular Disorders/physiopathology , Hemodynamics , Humans , MethodsABSTRACT
The paper outlines the diagnostic potentialities of the first Russian multidetector Testascan gamma-tomograph. With this, three different radio pharmaceuticals (RP) were used; 99mTC-GM PAO for examining cerebral circulatory disorders, 99mTC pertechnetate for visualizing tumor foci, and 99mTC-DTPK for studying impaired cerebral liquor pathway. Regional cerebral blood supply was studied in 78 patients with arterial aneurysms and arteriovenous malformations, with stenoses and thromboses of the great arterial trunks, as well in patients with brain injury sequelae and hypophyseal, craniofascial, and cavernous sinus tumors, VIII-neurinomas, meningiomas of the pyramid of the temporal bone. Some 103 patients with various intra- and extracerebral volumetric formations are examined. The impaired cerebral liquor pathways were explored in 27 patients with pathological processes of various genesis. Experience in clinically using the Russian Testascan computer gamma-tomograph in neurosurgical care has shown its high validity in diagnosing various focal processes of tumor and nontumor genesis. Single photon emission computerized tomography (SPECT) may reveal foci of abnormal elevation or reduction of RP accumulation by showing different anatomically topographic characteristics. SPECT is the most promising in the study of cerebrovascular diseases of various genesis and in the presence of tumors at basal sites.
Subject(s)
Brain Diseases/diagnostic imaging , Brain Injuries/diagnostic imaging , Gamma Cameras , Tomography, Emission-Computed, Single-Photon/instrumentation , Brain/diagnostic imaging , Brain Diseases/surgery , Brain Injuries/surgery , Humans , Microcomputers , Organotechnetium Compounds , Oximes , Sodium Pertechnetate Tc 99m , Technetium Tc 99m Exametazime , Technetium Tc 99m PentetateSubject(s)
Tomography, Emission-Computed , Tomography, X-Ray Computed , Medicine , Specialization , USSRABSTRACT
The authors presented clinical material on cerebral hemodynamics in patients with neurological pathology in suspected tumor vascular cerebral diseases and craniocerebral traumas. Investigation of cerebral microcirculation was performed using a multidetector single-photon emission tomograph "Testoscan" (USSR) after iv administration of 99mTc-hexamethylpropilene-amyloxine. This radiopharmaceutical is good for the evaluation of cerebral perfusion and gives a clinician rich information on cerebral microcirculation.
Subject(s)
Cerebrovascular Circulation , Head/diagnostic imaging , Organotechnetium Compounds , Oximes , Tomography, Emission-Computed, Single-Photon/methods , Adult , Aged , Cerebrovascular Disorders/diagnostic imaging , Drug Evaluation , Humans , Intracranial Aneurysm/diagnostic imaging , Ischemic Attack, Transient/diagnostic imaging , Microcirculation/diagnostic imaging , Middle Aged , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-Photon/instrumentationABSTRACT
The paper is concerned with the results of single-photon emission tomography and gamma-topography in patients with cerebral tumors, cerebral circulatory disorders and pathology of the liquor system. Tomographic investigation was shown to enhance the accuracy and reliability of the detection of cerebral tumors. Single-photon emission computerized gamma-tomography (SPECT) permitted the detection of structural and morphological cerebral changes in disturbed cerebral circulation of various etiology. SPECT together with computerized tomography and radionuclide cisternography was shown to be an auxiliary method for visualization of the cerebral cisterns. Radionuclide tomographic images as compared to gamma-topographic findings of the brain possessed a high statistical significance and good resolution.
Subject(s)
Brain Neoplasms/diagnostic imaging , Cerebrospinal Fluid/diagnostic imaging , Cerebrovascular Disorders/diagnostic imaging , Tomography, Emission-Computed, Single-Photon/instrumentation , Adult , Brain/diagnostic imaging , Evaluation Studies as Topic , Female , Humans , Male , Middle Aged , Organotechnetium Compounds , Oximes , Sodium Pertechnetate Tc 99m , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-Photon/methodsABSTRACT
The paper concerns adsorbents with different porosity intended for adsorption of gaseous 133Xe from the flow of a gas-air mixture exhaled by the patient undergoing the diagnosis, for instance, of the pulmonary system or cerebral blood flow. The data obtained were visualized on a gamma-chamber. An adsorbent exhibiting the highest adsorption capacity was selected. It has been shown that transport porosity of adsorbents does not play any significant role in adsorption of gaseous 133Xe. During adsorption, a much greater role is played by binding energy.
Subject(s)
Xenon Radioisotopes , Adsorption , Carbon , Humans , Xenon Radioisotopes/pharmacokineticsABSTRACT
A study was made of the cerebral hemodynamics by assessing the distribution in single-photon emission computerized tomography with 99mTc-hexamethyl-propyleneminoxyne in health using a Testascan in 9 standard slices. The whole set of tomographic slices was conventionally divided into 3 levels. For better orientation in gamma-tomographic images, pictures were presented where in addition to scintigrams a morphological scheme of the cerebral parts with the marked parts perfused by cerebral arteries, was given.
Subject(s)
Brain/diagnostic imaging , Cerebrovascular Circulation , Organotechnetium Compounds , Oximes , Tomography, Emission-Computed, Single-Photon/methods , Brain/blood supply , Brain Neoplasms/diagnostic imaging , Brain Neoplasms/physiopathology , Cerebrovascular Circulation/physiology , Cerebrovascular Disorders/diagnostic imaging , Cerebrovascular Disorders/physiopathology , Contrast Media , Hemodynamics/physiology , Humans , Technetium Tc 99m Exametazime , Tomography, Emission-Computed, Single-Photon/instrumentationABSTRACT
The mechanism of compensation for disorders of ventilation after pulmonary tissue resection is discussed. It is shown that these disorders are attended with reduction of arterial pulmonary blood flow and that angiospasm occurs in the postcapillary part of the vascular channel of pulmonary circulation. The compensatory effect is achieved by a right-to-right arteriovenous shunt which prevents extreme increase of pressure in the pulmonary artery in ventilation disorders.
Subject(s)
Arteriovenous Shunt, Surgical/methods , Lung Diseases/surgery , Pulmonary Artery/surgery , Pulmonary Veins/surgery , Ventilation-Perfusion Ratio , Adolescent , Adult , Female , Humans , Lung Diseases/diagnostic imaging , Lung Diseases/physiopathology , Male , Middle Aged , Pneumonectomy , Postoperative Complications/diagnostic imaging , Postoperative Complications/physiopathology , Postoperative Complications/surgery , Pulmonary Artery/diagnostic imaging , Pulmonary Artery/physiopathology , Pulmonary Circulation/physiology , Pulmonary Veins/diagnostic imaging , Pulmonary Veins/physiopathology , Radionuclide Imaging , Ventilation-Perfusion Ratio/physiologyABSTRACT
A TESTASCAN single-photon emission multidetector gamma tomograph is a special purpose unit designed to investigate RP distribution in the brain. It permits obtaining transversal tomographic images with the resolution of about 10 mm, the thickness of an emitted layer being about 15 mm. The time of patient's examination during obtaining an image of 10-12 layers does not exceed 30 min. and can be reduced by increasing RP activity and minimizing the number of emitted transversal sections. The clinical testing of the unit has shown that it is reliable in maintenance and simple to operate during radionuclide data collection, reproduction and analysis. Emission computerized tomography in brain tumors can be regarded as a method increasing the accuracy and reliability of radionuclide diagnostic examination of neurosurgical and neurological patients.
Subject(s)
Tomography, Emission-Computed/instrumentation , Brain Neoplasms/diagnostic imaging , Encephalitis/diagnostic imaging , Equipment Design , Evaluation Studies as Topic , Humans , Models, Structural , Sodium Pertechnetate Tc 99m , Tomography, Emission-Computed/methodsABSTRACT
Examinations of the muscle blood flow in the face have shown that this method may be used as one of the criteria in the objective evaluation of pain and for the follow-up of its severity in patients with trigeminal injury.
Subject(s)
Facial Muscles/blood supply , Trigeminal Neuralgia/physiopathology , Adult , Aged , Blood Flow Velocity , Female , Humans , Male , Middle Aged , Regional Blood FlowSubject(s)
Exocrine Glands/metabolism , Hormones/analysis , Radioimmunoassay/instrumentation , Diagnosis , Female , Georgia (Republic) , Humans , MaleSubject(s)
Asthma/surgery , Oxygen , Respiration , Adult , Denervation , Female , Humans , Male , Middle AgedABSTRACT
Visualization of the myocardial necrotic focus with the aid of 99mTc -pyrophosphate is an informative method of determining the infarction degree and localization in the cardiac muscle. Scanning enables evaluation of the area of the necrotic focus in patients with acute myocardial infarction within two weeks of the disease onset. Scintigraphy with both the diffuse and the focal variants of isotope accumulation is shown to be of high diagnostic value in acute myocardial infarction. The specificity and sensitivity of scintigraphy are 87% and 96%, respectively.
Subject(s)
Diphosphates , Myocardial Infarction/diagnostic imaging , Technetium , Aged , Female , Humans , Male , Middle Aged , Prognosis , Radionuclide Imaging , Technetium Tc 99m Pyrophosphate , Time FactorsABSTRACT
Forty-one patients with dyscirculatory encephalopathy complicated by a transient impairment of the cerebral circulation were examined in a neurological department. A comparative analysis of the findings obtained during comprehensive study of the cerebral circulation showed that in the overwhelming majority of cases (37 out of 41), the results of isotope angiography and rheography coincided and corresponded to the clinical findings. To a certain degree these methods complemented each other: rheoencephalography was more informative in the diagnosis of cerebral atherosclerosis and essential hypertension while radioisotope angiography allowed a more accurate determination of the area affected.