1.
Biull Eksp Biol Med
; 107(4): 451-3, 1989 Apr.
Article
in Russian
| MEDLINE
| ID: mdl-2720164
ABSTRACT
The capability of liposomes with plant phosphatidylcholine to extract cholesterol from erythrocyte membrane was investigated. It was shown, that plant phosphatidylcholine extracted 42% of membrane cholesterol, without causing haemolysis. This cholesterol extraction was responsible for the decrease of membrane microviscosity and for the increase of Na+, K+-ATPase activity. It is suggested that it is possible to create the extractive agent of cholesterol with plant phosphatidylcholine.
Subject(s)
Anticholesteremic Agents/pharmacology , Cholesterol/isolation & purification , Membrane Lipids/isolation & purification , Phosphatidylcholines/pharmacology , Animals , Cholesterol/blood , Drug Carriers , Drug Design , Drug Stability , Emulsions , Erythrocyte Membrane/drug effects , Erythrocyte Membrane/metabolism , Liposomes , Membrane Lipids/blood , Rabbits
2.
Lab Delo
; (10): 615-8, 1986.
Article
in Russian
| MEDLINE
| ID: mdl-2432323