Detection of Blood Glucose With Hemoglobin Content Using Compact Photonic Crystal Fiber.

We have proposed Twin Elliptical Core Photonic Crystal Fiber (TEC-PCF) sensor for the detection of blood glucose level under the influence of hemoglobin components. The main featuring of the proposed biosensor is to detect the wide range of blood glucose content with enhanced sensitivity, by utilizing small length of the fiber. In order to achieve this, we have constructed asymmetric TEC-PCF where the elliptical core is filled by blood sample. The numerical sensing characteristics are evaluated using Finite Element Method (FEM). By varying hemoglobin concentrations as 120 g/L, 140 g/L and 160 g/L, we realize enhanced blood glucose sensing with detection range from 0 g/L to 100 g/L. The sensing performance of the proposed biosensor is studied through the coupling length and transmission power spectrum by calculation of effective index of the coupling mode. The obtained maximum wavelength sensitivity under the influence of 160 g/L hemoglobin content is 2.4 nm/(g/L) and 2.42 nm/(g/L) with fiber length of 0.245 mm and 0.215 mm for X and Y polarization, respectively. Further, limit of detection (LOD) is calculated under the influence of 160 g/L hemoglobin content is 0.375 mg/L and 0.372 mg/L for X and Y polarization, respectively. The proposed miniaturized sensing device can be integrated with microfluidic systems for the development of next-generation biosensor applications as point of- care and lab-on-a-chip.

Efficacy analysis of LDPC coded APSK modulated differential space-time-frequency coded for wireless body area network using MB-pulsed OFDM UWB technology.

Wireless body area network (WBAN) is a breakthrough technology in healthcare areas such as hospital and telemedicine. The human body has a complex mixture of different tissues. It is expected that the nature of propagation of electromagnetic signals is distinct in each of these tissues. This forms the base for the WBAN, which is different from other environments. In this paper, the knowledge of Ultra Wide Band (UWB) channel is explored in the WBAN (IEEE 802.15.6) system. The measurements of parameters in frequency range from 3.1-10.6 GHz are taken. The proposed system, transmits data up to 480 Mbps by using LDPC coded APSK Modulated Differential Space-Time-Frequency Coded MB-OFDM to increase the throughput and power efficiency.

Synthesis of silver nanoparticles using leaves of Catharanthus roseus Linn. G. Don and their antiplasmodial activities.

OBJECTIVE: To develop a novel approach for the green synthesis of silver nanoparticles using aqueous leaves extracts of Catharanthus roseus (C. roseus) Linn. G. Don which has been proven active against malaria parasite Plasmodium falciparum (P. falciparum). METHODS: Characterizations were determined by using ultraviolet-visible (UV-Vis) spectrophotometry, scanning electron microscopy (SEM), energy dispersive X-ray and X-ray diffraction. RESULTS: SEM showed the formation of silver nanoparticles with an average size of 35-55 nm. X-ray diffraction analysis showed that the particles were crystalline in nature with face centred cubic structure of the bulk silver with the broad peaks at 32.4, 46.4 and 28.0. CONCLUSIONS: It can be concluded that the leaves of C. roseus can be good source for synthesis of silver nanoparticle which shows antiplasmodial activity against P. falciparum. The important outcome of the study will be the development of value added products from medicinal plants C. roseus for biomedical and nanotechnology based industries.