ABSTRACT
AIM: To evaluate different dosages of vasoactive drug viagra in patients with erectile dysfunction suffering from diabetes mellitus (DM) type I and II. MATERIALS AND METHODS: Viagra in doses 25, 50 and 100 mg was given to 30 DM patients with different forms of erectile dysfunction. RESULTS: The response was obtained in 70.3% of cases. The highest effect was achieved with the dose 100 mg (the response rate 68.5% of patients). The dose 50 mg was effective in 31.5%, 25 mg in 0% of patients. Most nonresponders had low testosterone levels in the blood.
Subject(s)
3',5'-Cyclic-GMP Phosphodiesterases/antagonists & inhibitors , Diabetes Mellitus, Type 1/complications , Diabetes Mellitus, Type 2/complications , Erectile Dysfunction/drug therapy , Phosphodiesterase Inhibitors/administration & dosage , Piperazines/administration & dosage , Adult , Aged , Biomarkers/blood , Blood Glucose/metabolism , Diabetes Mellitus, Type 1/blood , Diabetes Mellitus, Type 2/blood , Dose-Response Relationship, Drug , Erectile Dysfunction/blood , Erectile Dysfunction/complications , Humans , Male , Middle Aged , Phosphodiesterase Inhibitors/therapeutic use , Piperazines/therapeutic use , Purines , Sildenafil Citrate , Sulfones , Testosterone/blood , Treatment OutcomeABSTRACT
Epidemiological situation (1989-1993) in relation to tuberculosis has been analyzed for the Khabarovsk region. The data support epidemiological significance of M. tuberculosis drug resistance which implies the leading role of exogenic mechanism in tuberculosis development. Tuberculosis occurrence in city population tends to increase. The number of subjects discharging drug-resistant M. tuberculosis has increased by 28%. Contact with tuberculosis patients may be responsible for new cases discharging drug-resistant M. tuberculosis in 56.3%.
