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2.
Khirurgiia (Mosk) ; (6): 98-103, 1990 Jun.
Article in Russian | MEDLINE | ID: mdl-2214587

ABSTRACT

Intravenous infusion of perfluorocarbon emulsion (PFCE) during autotransplantation of kidneys which had been stored for 24 hours led to a rapid normalization of intraorganic hemodynamics in dogs, and restoration of ionic homeostasis, energy potential, and functional activity of the transplants. It was shown that the protective effect of PFCE is associated with inhibition of free-radical lipid peroxidation, and the establishment of a stable protein-lipid conformation of the membrane structures of the cells of ischemic organs. It was established that the use of PFCE in the stage of stored kidney transplantation may be an effective method for the prevention of reperfusion damage to the transplant.


Subject(s)
Cryopreservation/methods , Fluorocarbons/administration & dosage , Kidney Transplantation/methods , Kidney/drug effects , Organ Preservation/methods , Reperfusion Injury/prevention & control , Animals , Dogs , Emulsions , Infusions, Intravenous , Kidney/physiology , Kidney/surgery , Kidney Transplantation/physiology , Time Factors , Transplantation, Autologous
3.
Biofizika ; 20(1): 121-5, 1975.
Article in Russian | MEDLINE | ID: mdl-1111602

ABSTRACT

Synchronization of two cells differing in sodium permeability has been studied. More frequent contractions of myocardial cells under synchronization described in [3], when the frequency of simultaneous excitation of cells is higher than that of each of them before the contact, can be explained by the electrical properties of the membranes of myocardial cells.


Subject(s)
Heart Conduction System/physiology , Action Potentials , Cell Membrane/physiology , Cell Membrane Permeability , Intercellular Junctions/physiology , Models, Biological
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