ABSTRACT
The article is devoted to the review of main directions of anti-shock therapy improvement for patients with severe burns. It is shown that the treatment efficiency can be considerably increased both by optimization of infusion volume and by the use of modern infusion drugs with anti-hypoxic and anti-oxidant effects. The use of anti-hypoxic and anti-oxidant drugs permits to change the burn shock course and to decrease its duration. Decrease in severity of tissue hypoxia, prevention of cellular membrane injury interrupt one of the circuits of burn disease pathogenesis and create the favorable conditions for realization of acute adaptation mechanisms in terms of traumatic disease conception. The modern schemes of anti-shock therapy approved at the department of thermal injuries were used in the treatment of casualties with combined burns after the armed conflict in the territory of Chechnia (1999-2001).
Subject(s)
Analgesics/therapeutic use , Antioxidants/therapeutic use , Burns/therapy , Fluid Therapy , Shock, Traumatic/therapy , Analgesics/administration & dosage , Antioxidants/administration & dosage , Burns/complications , Burns/metabolism , Humans , Lipid Peroxidation/drug effects , Shock, Traumatic/etiology , Shock, Traumatic/metabolismABSTRACT
The article proposes a standard model of the present-day gunshot wound for an experimental investigation of the wound process in small laboratory animals. It is shown that the microwave therapy of mild intensity is an expedient method to provide a noncomplicated course of the wound process and adequate regeneration of the tissues in complex treatment of gunshot wounds of soft tissues and burns of extremities.