ABSTRACT
Seventy-eight patients with acute neurotropic poisoning (soporifics, neuroleptics, antidepressants, ethanol and its surrogates, narcotics) were examined and treated. Study of the pathogenesis of hypoxic injuries in acute neurotropic poisoning demonstrated the efficiency of using Perfluorane, an infusion solution with oxygen transporting functions, and Cytoflavine, a substrate antihypoxant, for correction of the detected disorders.
Subject(s)
Central Nervous System Depressants/poisoning , Coma/chemically induced , Critical Care , Fluorocarbons/therapeutic use , Hypoxia/etiology , Oxygen/metabolism , Poisoning/therapy , Psychotropic Drugs/poisoning , Acute Disease , Alcoholic Intoxication , Antidepressive Agents/poisoning , Antipsychotic Agents/poisoning , Coma/complications , Female , Fluorocarbons/administration & dosage , Humans , Hypnotics and Sedatives/poisoning , Hypoxia/drug therapy , Male , Narcotics/poisoning , Oxygen Consumption , Statistics, NonparametricABSTRACT
Under analysis there were 104 case histories of patients with surgical diseases diagnosed in a toxicological center. In 34 patients the surgical diseases or mechanical traumas were combined with poisoning, in 106 patients they appeared due to acute poisoning. In the first group most frequent were closed craniocerebral injuries and acute destructive pancreatitis. In the second group prevailing were gastroesophageal bleedings.
