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Afr Health Sci ; 20(2): 597-604, 2020 Jun.
Article in English | MEDLINE | ID: mdl-33163020

ABSTRACT

BACKGROUND: Saliva is a complex secretion produced daily by the salivary glands. Saliva consists mainly of water, enzymes, ions and amino acids and performs several important functions in oral health. OBJECTIVE: The aim of this study was to investigate the flow rate and concentrations of amylase and total proteins in the saliva of hospitalized patients due to AIDS complications. METHODS: Ninety-three men and women (20-64 years of age) were divided into two groups (46 HIV-infected patients and 47 controls) and had salivary flow rate and levels of amylase enzyme and total proteins evaluated. RESULT: The mean salivary flow rate was lower in individuals with HIV when compared to controls (P < 0.05). No significant difference between amylase enzyme levels and total proteins were observed in the saliva of patients with HIV infection when compared to controls. CONCLUSION: Individuals with HIV / AIDS infection (in hospital treatment) suffer no interference in levels of amylase and total salivary proteins, but they have significantly reduced salivary flow.


Subject(s)
HIV Infections/complications , HIV Seropositivity/complications , Saliva/metabolism , Salivary Proteins and Peptides/metabolism , Salivation/physiology , Xerostomia/complications , alpha-Amylases/metabolism , Adolescent , Adult , Aged , Amylases/analysis , Amylases/metabolism , Anti-HIV Agents/therapeutic use , Antiretroviral Therapy, Highly Active/adverse effects , Case-Control Studies , Female , HIV Infections/blood , HIV Infections/drug therapy , HIV Seropositivity/drug therapy , Humans , Male , Middle Aged , Salivary Glands/metabolism , Salivary Proteins and Peptides/analysis , Secretory Rate/drug effects , Secretory Rate/physiology , Xerostomia/etiology , Young Adult , alpha-Amylases/analysis
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